2npc

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==An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance==
==An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance==
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<StructureSection load='2npc' size='340' side='right' caption='[[2npc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='2npc' size='340' side='right'caption='[[2npc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2npc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NPC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2npc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NPC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xqf|1xqf]], [[1xqe|1xqe]], [[1u7g|1u7g]], [[2nmr|2nmr]], [[2nop|2nop]], [[2now|2now]], [[2npd|2npd]], [[2npe|2npe]], [[2npg|2npg]], [[2npj|2npj]], [[2npk|2npk]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xqf|1xqf]], [[1xqe|1xqe]], [[1u7g|1u7g]], [[2nmr|2nmr]], [[2nop|2nop]], [[2now|2now]], [[2npd|2npd]], [[2npe|2npe]], [[2npg|2npg]], [[2npj|2npj]], [[2npk|2npk]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amtB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2npc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2npc OCA], [http://pdbe.org/2npc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2npc RCSB], [http://www.ebi.ac.uk/pdbsum/2npc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2npc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2npc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2npc OCA], [https://pdbe.org/2npc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2npc RCSB], [https://www.ebi.ac.uk/pdbsum/2npc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2npc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AMTB_ECOLI AMTB_ECOLI]] Involved in the uptake of ammonia.
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[[https://www.uniprot.org/uniprot/AMTB_ECOLI AMTB_ECOLI]] Involved in the uptake of ammonia.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2npc_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2npc_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2npc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2npc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
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[[Category: Large Structures]]
[[Category: Lupo, D]]
[[Category: Lupo, D]]
[[Category: Winkler, F K]]
[[Category: Winkler, F K]]

Revision as of 15:47, 8 June 2021

An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance

PDB ID 2npc

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