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2pji
From Proteopedia
(Difference between revisions)
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==Solution structure of rhodostomin P48A mutant== | ==Solution structure of rhodostomin P48A mutant== | ||
| - | <StructureSection load='2pji' size='340' side='right' caption='[[2pji]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2pji' size='340' side='right'caption='[[2pji]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pji]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2pji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agkistrodon_rhodostoma Agkistrodon rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaz 1xaz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PJI FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pji OCA], [https://pdbe.org/2pji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pji RCSB], [https://www.ebi.ac.uk/pdbsum/2pji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pji ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Agkistrodon rhodostoma]] | [[Category: Agkistrodon rhodostoma]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chuang, W J]] | [[Category: Chuang, W J]] | ||
[[Category: Liu, Y C]] | [[Category: Liu, Y C]] | ||
Current revision
Solution structure of rhodostomin P48A mutant
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