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Cytochrome P450
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== Function == | == Function == | ||
| - | [[Cytochrome P450]] (P450) catalyzes the oxidation of organic substances like lipids. The P450 contains a heme cofactor. The protein is numbered by its gene.<ref>PMID:12369887</ref>.<br /> | + | [[Cytochrome P450]] (P450) or '''cytochrome P450 monooxygenase''' catalyzes the oxidation of organic substances like lipids. The P450 contains a heme cofactor. The protein is numbered by its gene.<ref>PMID:12369887</ref>.<br /> |
* '''P450cam''', also known as camphor 5-monooxygenase, catalyzes the hydroxylation of camphor.<br /> | * '''P450cam''', also known as camphor 5-monooxygenase, catalyzes the hydroxylation of camphor.<br /> | ||
* '''P450nor''' is a Nitric Oxide Reductase P450.<br /> | * '''P450nor''' is a Nitric Oxide Reductase P450.<br /> | ||
Revision as of 09:30, 22 June 2021
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References
- ↑ Danielson PB. The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metab. 2002 Dec;3(6):561-97. PMID:12369887
- ↑ Williams PA, Cosme J, Ward A, Angove HC, Matak Vinkovic D, Jhoti H. Crystal structure of human cytochrome P450 2C9 with bound warfarin. Nature. 2003 Jul 24;424(6947):464-8. Epub 2003 Jul 13. PMID:12861225 doi:http://dx.doi.org/10.1038/nature01862
