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2qsr

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==Crystal structure of C-terminal domain of transcription-repair coupling factor==
==Crystal structure of C-terminal domain of transcription-repair coupling factor==
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<StructureSection load='2qsr' size='340' side='right' caption='[[2qsr]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<StructureSection load='2qsr' size='340' side='right'caption='[[2qsr]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qsr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strr6 Strr6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QSR FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QSR FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qsr OCA], [https://pdbe.org/2qsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qsr RCSB], [https://www.ebi.ac.uk/pdbsum/2qsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qsr ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2qsr TOPSAN]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mfd, spr0006 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 STRR6])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qsr OCA], [http://pdbe.org/2qsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qsr RCSB], [http://www.ebi.ac.uk/pdbsum/2qsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qsr ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2qsr TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/Q8DRQ1_STRR6 Q8DRQ1_STRR6]] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (By similarity).[HAMAP-Rule:MF_00969]
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qsr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qsr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qsr ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qsr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Transcription-repair coupling factor|Transcription-repair coupling factor]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Strr6]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Bain, K]]
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[[Category: Bain K]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Gilmore, M]]
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[[Category: Gilmore M]]
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[[Category: Iizuka, M]]
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[[Category: Iizuka M]]
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[[Category: Structural genomic]]
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[[Category: Ramagopal UA]]
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[[Category: Ramagopal, U A]]
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[[Category: Rodgers L]]
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[[Category: Rodgers, L]]
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[[Category: Sauder JM]]
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[[Category: Sauder, J M]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Wasserman S]]
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[[Category: Wasserman, S]]
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[[Category: Atp-binding]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide-binding]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transcription]]
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[[Category: Transcription-repair]]
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Current revision

Crystal structure of C-terminal domain of transcription-repair coupling factor

PDB ID 2qsr

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