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2rfq

From Proteopedia

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[[Image:2rfq.gif|left|200px]]
 
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==Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1==
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The line below this paragraph, containing "STRUCTURE_2rfq", creates the "Structure Box" on the page.
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<StructureSection load='2rfq' size='340' side='right'caption='[[2rfq]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2rfq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhojr Rhojr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RFQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PS:3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE'>1PS</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_2rfq| PDB=2rfq | SCENE= }}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hsaA, RHA1_ro04539 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=101510 RHOJR])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfq OCA], [https://pdbe.org/2rfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rfq RCSB], [https://www.ebi.ac.uk/pdbsum/2rfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rfq ProSAT], [https://www.topsan.org/Proteins/MCSG/2rfq TOPSAN]</span></td></tr>
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'''Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1'''
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/HSAA_RHOSR HSAA_RHOSR]] Catalyzes the o-hydroxylation of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol.<ref>PMID:17264217</ref>
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==About this Structure==
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== Evolutionary Conservation ==
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2RFQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._rha1 Rhodococcus sp. rha1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFQ OCA].
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Rhodococcus sp. rha1]]
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Check<jmol>
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[[Category: Single protein]]
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<jmolCheckbox>
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[[Category: Chang, C.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rfq_consurf.spt"</scriptWhenChecked>
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[[Category: Edwards, A M.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Joachimiak, A.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Kagan, O.]]
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</jmolCheckbox>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rfq ConSurf].
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[[Category: Savchenko, A.]]
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<div style="clear:both"></div>
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[[Category: Skarina, T.]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rhojr]]
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[[Category: Chang, C]]
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[[Category: Edwards, A M]]
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[[Category: Joachimiak, A]]
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[[Category: Kagan, O]]
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[[Category: Structural genomic]]
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[[Category: Savchenko, A]]
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[[Category: Skarina, T]]
[[Category: 3-hsa hydroxylase]]
[[Category: 3-hsa hydroxylase]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Rhodococcus sp. rha1]]
[[Category: Rhodococcus sp. rha1]]
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[[Category: Structural genomic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 16:50:14 2008''
 

Current revision

Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1

PDB ID 2rfq

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