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1eu0

From Proteopedia

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{{Theoretical_model}}
{{Theoretical_model}}
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[[Image:1eu0.png|left|200px]]
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==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)==
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<StructureSection load='1eu0' size='340' side='right'caption='[[1eu0]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EU0 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eu0 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1eu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eu0 ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification.
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{{STRUCTURE_1eu0| PDB=1eu0 | SCENE= }}
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alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref>
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===THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_10812058}}
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<div class="pdbe-citations 1eu0" style="background-color:#fffaf0;"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010812058</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Theoretical Model]]
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[[Category: Large Structures]]
[[Category: Kajava, A V]]
[[Category: Kajava, A V]]

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)

PDB ID 1eu0

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