1eu0
From Proteopedia
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{{Theoretical_model}} | {{Theoretical_model}} | ||
| - | [[ | + | ==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)== |
| + | <StructureSection load='1eu0' size='340' side='right'caption='[[1eu0]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EU0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eu0 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1eu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eu0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification. | ||
| - | + | alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 1eu0" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Theoretical Model]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kajava, A V]] | [[Category: Kajava, A V]] | ||
Current revision
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THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)
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