Growth differentiation factor
From Proteopedia
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*'''GDF-11''' or '''bone morphogenetic protein 11''' is a circulating factor that reverses age-related cardiac hypertrophy<ref>PMID:23663781</ref>. | *'''GDF-11''' or '''bone morphogenetic protein 11''' is a circulating factor that reverses age-related cardiac hypertrophy<ref>PMID:23663781</ref>. | ||
*'''GDF-15''' or '''placental bone morphogenetic protein''' protects the hart from ischmia and reperfusion injury<ref>PMID:16484622</ref>. | *'''GDF-15''' or '''placental bone morphogenetic protein''' protects the hart from ischmia and reperfusion injury<ref>PMID:16484622</ref>. | ||
| - | + | See also [[Growth factors]] and [[Bone morphogenetic protein]]. | |
==3D structures of growth differentiation factor== | ==3D structures of growth differentiation factor== | ||
[[Growth differentiation factor 3D STRUCTURES]] | [[Growth differentiation factor 3D STRUCTURES]] | ||
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</StructureSection> | </StructureSection> | ||
| - | ==3D structures of growth differentiation factor== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *GDF-2 | ||
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| - | **[[1zkz]], [[4mpl]], [[5i05]] – hGDF residues 320-493 – human <br /> | ||
| - | **[[4fao]] – hGDF residues 320-493 + serine/threonine-protein kinase receptor + activin receptor<br /> | ||
| - | **[[5hzw]] – hGDF residues 320-493 + MBP/endoglin <br /> | ||
| - | **[[4ycg]], [[4yci]] – mGDF residues 23-318 + hGDF residues 320-493 - mouse<br /> | ||
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| - | *GDF-5 | ||
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| - | **[[2bhk]], [[1waq]] – hGDF <br /> | ||
| - | **[[3evs]] – hGDF + bone morphogenetic receptor <br /> | ||
| - | **[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor <br /> | ||
| - | **[[5hk5]] – hGDF + gremlin-2 <br /> | ||
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| - | *GDF-8 | ||
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| - | **[[5ji1]] – mGDF – mouse <br /> | ||
| - | **[[3hh2]] – mGDF + follistatin <br /> | ||
| - | **[[3sek]] – mGDF + follistatin-related protein <br /> | ||
| - | **[[5nsx]], [[5ntu]] – hGDF (mutant) <br /> | ||
| - | **[[5f3h]], [[5f3b]] – hGDF + antibody <br /> | ||
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| - | *GDF-11 | ||
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| - | **[[5uhm]], [[5e4g]] – hGDF <br /> | ||
| - | **[[5jhw]] – hGDF + follistatin <br /> | ||
| - | **[[6mac]] – hGDF + activing receptor + TGF-b receptor <br /> | ||
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| - | *GDF-15 | ||
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| - | **[[5vz3]], [[5vt2]] – hGDF <br /> | ||
| - | **[[5vz4]] – hGDF + GDNF family receptor a-like <br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73. PMID:23432680
- ↑ Ferrell RE, Conte V, Lawrence EC, Roth SM, Hagberg JM, Hurley BF. Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics. 1999 Dec 1;62(2):203-7. PMID:10610713 doi:http://dx.doi.org/10.1006/geno.1999.5984
- ↑ Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013 May 9;153(4):828-39. doi: 10.1016/j.cell.2013.04.015. PMID:23663781 doi:http://dx.doi.org/10.1016/j.cell.2013.04.015
- ↑ Ago T, Sadoshima J. GDF15, a cardioprotective TGF-beta superfamily protein. Circ Res. 2006 Feb 17;98(3):294-7. doi: 10.1161/01.RES.0000207919.83894.9d. PMID:16484622 doi:http://dx.doi.org/10.1161/01.RES.0000207919.83894.9d
