Galectin 3D structures

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Line 10: Line 10:
**[[2km2]] – hGAL-1 - NMR<BR />
**[[2km2]] – hGAL-1 - NMR<BR />
**[[1w6n]], [[1w6q]] - hGAL-1 (mutant) <br />
**[[1w6n]], [[1w6q]] - hGAL-1 (mutant) <br />
-
**[[1w6o]], [[2zkn]] – hGAL-1 (mutant) + lactose<br />
+
**[[1w6o]], [[2zkn]], [[6m5y]] – hGAL-1 (mutant) + lactose<br />
**[[4q26]], [[4q27]], [[4xbl]] - hGAL-1 + acetyl lactosamine<br />
**[[4q26]], [[4q27]], [[4xbl]] - hGAL-1 + acetyl lactosamine<br />
**[[6b94]] - hGAL-1 + lactulose<br />
**[[6b94]] - hGAL-1 + lactulose<br />
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**[[1ule]], [[1ulf]] – CcGAL-2 + polysaccharide<br />
**[[1ule]], [[1ulf]] – CcGAL-2 + polysaccharide<br />
-
*Galectin-3
+
*Galectin-3; Domain – CRD 113-250
**[[3zsk]], [[3zsl]], [[3zsm]], [[6exy]], [[5nfc]], [[6h64]] – hGAL-3 CRD<br />
**[[3zsk]], [[3zsl]], [[3zsm]], [[6exy]], [[5nfc]], [[6h64]] – hGAL-3 CRD<br />
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**[[1a3k]], [[1kjl]], [[2nmn]] – hGAL-3 CRD + BGAL<br />
**[[1a3k]], [[1kjl]], [[2nmn]] – hGAL-3 CRD + BGAL<br />
**[[2nmo]] - hGAL-3 CRD + glucose + BGAL<br />
**[[2nmo]] - hGAL-3 CRD + glucose + BGAL<br />
-
**[[2nn8]], [[3aye]], [[3zsj]], [[4r9a]], [[4r9b]], [[4r9c]], [[4r9d]], [[4rl7]], [[6eym]], [[6y4c]] - hGAL-3 CRD + lactose<br />
+
**[[2nn8]], [[3aye]], [[3zsj]], [[4r9a]], [[4r9b]], [[4r9c]], [[4r9d]], [[4rl7]], [[6eym]], [[6y4c]], [[6y78]] - hGAL-3 CRD + lactose<br />
-
**[[1kjr ]], [[4xbn]], [[5nf7]], [[5nf9]], [[5nla]], [[5nlb]], [[5nfb]], [[5nfa]] - hGAL-3 CRD + lactosamine derivative<br />
+
**[[1kjr]], [[4xbn]], [[5nf7]], [[5nf9]], [[5nla]], [[5nlb]], [[5nfb]], [[5nfa]] - hGAL-3 CRD + lactosamine derivative<br />
 +
**[[7be3]] - hGAL-3 CRD + lactose derivative<br />
**[[2xg3]], [[3t1l]], [[3t1m]], [[5e88]], [[5e89]], [[5e8a]], [[5exo]], [[5h9p]], [[5h9r]], [[5iuq]], [[6q0q]], [[6q17]] - hGAL-3 CRD + inhibitor<br />
**[[2xg3]], [[3t1l]], [[3t1m]], [[5e88]], [[5e89]], [[5e8a]], [[5exo]], [[5h9p]], [[5h9r]], [[5iuq]], [[6q0q]], [[6q17]] - hGAL-3 CRD + inhibitor<br />
**[[3aya]], [[6g0v]] - hGAL-3 CRD + antigen<br />
**[[3aya]], [[6g0v]] - hGAL-3 CRD + antigen<br />
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**[[4lbj]], [[4lbk]], [[4lbl]], [[4lbm]], [[4lbn]], [[4lbo]] - hGAL-3 CRD (mutant) + glycosphingolipid<br />
**[[4lbj]], [[4lbk]], [[4lbl]], [[4lbm]], [[4lbn]], [[4lbo]] - hGAL-3 CRD (mutant) + glycosphingolipid<br />
**[[4bli]], [[4blj]], [[4bm8]], [[5oax]], [[5ody]], [[6i74]], [[6i75]], [[6i76]], [[6i77]], [[6i78]] - hGAL-3 CRD + thiogalactoside derivative<br />
**[[4bli]], [[4blj]], [[4bm8]], [[5oax]], [[5ody]], [[6i74]], [[6i75]], [[6i76]], [[6i77]], [[6i78]] - hGAL-3 CRD + thiogalactoside derivative<br />
-
**[[6eol]], [[6eog]] - hGAL-3 CRD + galactose derivative<br />
+
**[[6eol]], [[6eog]], [[6tf6]], [[6tf7]] - hGAL-3 CRD + galactose derivative<br />
**[[6qge]], [[6qgf]] - hGAL-3 CRD + ligand<br />
**[[6qge]], [[6qgf]] - hGAL-3 CRD + ligand<br />
**[[6fk2]] - hGAL-3 CRD + lactitol<br />
**[[6fk2]] - hGAL-3 CRD + lactitol<br />
**[[6b8k]] - hGAL-3 CRD + lactulose<br />
**[[6b8k]] - hGAL-3 CRD + lactulose<br />
**[[6qln]], [[6qlo]], [[6qlp]], [[6qlq]], [[6qlr]], [[6qls]], [[6qlt]], [[6qlu]], [[6rhl]], [[6rhm]], [[6rzf]], [[6rzg]], [[6rzh]], [[6rzi]], [[6rzj]], [[6rzk]], [[6rzl]], [[6rzm]] - hGAL-3 CRD + fluoroaryl monogalactoside derivative<br />
**[[6qln]], [[6qlo]], [[6qlp]], [[6qlq]], [[6qlr]], [[6qls]], [[6qlt]], [[6qlu]], [[6rhl]], [[6rhm]], [[6rzf]], [[6rzg]], [[6rzh]], [[6rzi]], [[6rzj]], [[6rzk]], [[6rzl]], [[6rzm]] - hGAL-3 CRD + fluoroaryl monogalactoside derivative<br />
 +
**[[7df6]] - mGAL-3 CRD + inhibitor<br />
-
*Galectin-4
+
*Galectin-4; Domains – N-terminal CRD 1-155; C-terminal CRD 173-323
-
**[[1x50]] – hGAL-4 CRD – NMR<BR />
+
**[[1x50]] – hGAL-4 C-terminal CRD – NMR<BR />
-
**[[4xzp]], [[5duu]] - hGAL-4 N terminal <br />
+
**[[4xzp]], [[5duu]] - hGAL-4 N terminal CRD<br />
-
**[[5duv]], [[5duw]], [[5dux]] - hGAL-4 N terminal + lactose derivative<br />
+
**[[5duv]], [[5duw]], [[5dux]] - hGAL-4 N terminal CRD+ lactose derivative<br />
-
**[[4ylz]], [[4ym0]] - hGAL-4 CRD + lacto-neotetraose<br />
+
**[[4ylz]], [[4ym0]] - hGAL-4 C-terminal CRD + lacto-neotetraose<br />
-
**[[4ym1]], [[4ym2]], [[4ym3]], [[5cbl]] - hGAL-4 CRD + lactose derivative<br />
+
**[[4ym1]], [[4ym2]], [[4ym3]], [[5cbl]] - hGAL-4 C-terminal CRD + lactose derivative<br />
-
**[[2dyc]] – mGAL-4 CRD <br />
+
**[[6wab]] - hGAL-4 C-terminal CRD + galactose derivative<br />
-
**[[3i8t]] – mGAL-4 + lactose<br />
+
**[[2dyc]] – mGAL-4 N-terminal CRD <br />
 +
**[[3i8t]] – mGAL-4 N-terminal CRD + lactose<br />
-
*Galectin-5
+
*Galectin-5; Residues 1-136
**[[5jp5]] – rGAL-5<br />
**[[5jp5]] – rGAL-5<br />
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**[[4y26]] - hGAL-7 N-terminal + Gal-GlcNac<br />
**[[4y26]] - hGAL-7 N-terminal + Gal-GlcNac<br />
-
*Galectin-8
+
*Galectin-8; Domains – N-terminal CRD 1-154; C-terminal CRD 175-315
-
**[[2yro]] – hGAL-8 CRD – NMR<BR />
+
**[[2yro]] – hGAL-8 C-terminal CRD – NMR<BR />
-
**[[3ap5]], [[3apb]], [[3ap9]], [[3vkn]] - hGAL-8 CRD<br />
+
**[[3ap5]], [[3apb]], [[3ap9]], [[3vkn]] - hGAL-8 N-terminal CRD<br />
-
**[[3ap4]], [[3ap6]], [[3vkl]] - hGAL-8 CRD + lactose<br />
+
**[[3ap4]], [[3ap6]], [[3vkl]] - hGAL-8 N-terminal CRD + lactose<br />
-
**[[3ap7]], [[3vkm]] - hGAL-8 CRD + sialyllactose<br />
+
**[[3ap7]], [[3vkm]] - hGAL-8 N-terminal CRD + sialyllactose<br />
-
**[[3ap8]], [[3vko]] - hGAL-8 CRD + polysaccharide<br />
+
**[[3ap8]], [[3vko]] - hGAL-8 N-terminal CRD + polysaccharide<br />
-
**[[4gxl]], [[4han]] - hGAL-8 CRD + NDP52 peptide<br />
+
**[[4gxl]] - hGAL-8 C-terminal CRD + NDP52 peptide<br />
-
**[[4fqz]] – hGAL-8 CRD (mutant) + glucose + BGAL<br />
+
**[[4han]] - hGAL-8 N-terminal CRD+C-terminal CRD + NDP52 peptide<br />
-
**[[2yv8]], [[5gzc]], [[5gzd]], [[5gze]], [[5gzf]], [[5gzg]], [[5t7u]] – hGAL-8 N terminal<br />
+
**[[4fqz]] – hGAL-8 N-terminal CRD+C-terminal CRD (mutant) + glucose + BGAL<br />
-
**[[3ojb]] - hGAL-8 C terminal<br />
+
**[[2yv8]], [[5gzc]], [[5gzd]], [[5gze]], [[5gzf]], [[5gzg]], [[5t7u]] – hGAL-8 N terminal CRD<br />
-
**[[2yxs]], [[4bmb]] – hGAL-8 N terminal + lactose<br />
+
**[[3ojb]] - hGAL-8 C terminal CRD<br />
-
**[[4bme]], [[5t7s]] – hGAL-8 N terminal (mutant) + lactose<br />
+
**[[2yxs]], [[4bmb]] – hGAL-8 N terminal CRD + lactose<br />
-
**[[5t7i]] – hGAL-8 N terminal + LNNT<br />
+
**[[4bme]], [[5t7s]] – hGAL-8 N terminal CRD (mutant) + lactose<br />
-
**[[5t7t]] – hGAL-8 N terminal (mutant) + LNT<br />
+
**[[5t7i]] – hGAL-8 N terminal CRD + LNNT<br />
-
**[[2yy1]] – hGAL-8 N terminal + acetyllactosamine<br />
+
**[[5t7t]] – hGAL-8 N terminal CRD (mutant) + LNT<br />
-
**[[5vwg]] – hGAL-8 N terminal (mutant) + galactopyranoside derivative<br />
+
**[[2yy1]] – hGAL-8 N terminal CRD + acetyllactosamine<br />
-
**[[4wvv]], [[4wvw]] - cGAL-8 N terminal + lactose derivative<br />
+
**[[5vwg]], [[6w4z]] – hGAL-8 N terminal CRD (mutant) + galactopyranoside derivative<br />
 +
**[[6z6y]] – hGAL-8 N terminal CRD + sulfatide<br />
 +
**[[7aen]] – hGAL-8 N terminal CRD + galactopyranoside derivative <br />
 +
**[[4wvv]], [[4wvw]] - cGAL-8 N terminal CRD + lactose derivative<br />
-
*Galectin-9
+
*Galectin-9; Domains – N-terminal CRD 1-148; C-teminal CRD 186-323
-
**[[3lsd]] – hGAL-9 N terminal<br />
+
**[[3lsd]] – hGAL-9 N terminal CRD<br />
-
**[[3wv6]] – hGAL-9 (mutant)<br />
+
**[[3wv6]] – hGAL-9 N-terminal CRD+C-terminal CRD (mutant)<br />
-
**[[3nv1]] – hGAL-9 CRD<br />
+
**[[3nv1]] – hGAL-9 C terminal CRD<br />
-
**[[3lse]] – hGAL-9 N terminal + lactose<br />
+
**[[3lse]] – hGAL-9 N terminal CRD + lactose<br />
**[[2eak]], [[3wlu]] - hGAL-9 CRD + lactose<br />
**[[2eak]], [[3wlu]] - hGAL-9 CRD + lactose<br />
-
**[[3nv4]] - hGAL-9 CRD + sialyllactose<br />
+
**[[3nv4]] - hGAL-9 C-terminal CRD + sialyllactose<br />
-
**[[2zhk]], [[2zhl]], [[2zhm]], [[2zhn]], [[3nv2]] - hGAL-9 CRD + acetyllactosamine<br />
+
**[[2zhk]], [[2zhl]], [[2zhm]], [[2zhn]], [[3nv2]] - hGAL-9 N-terminal CRD + acetyllactosamine<br />
-
**[[3nv3]] - hGAL-9 CRD + polysaccharide<br />
+
**[[3nv2]] - hGAL-9 C-terminal CRD + acetyllactosamine<br />
-
**[[2eal]] - mGAL-9 CRD + pentasaccharide<br />
+
**[[3nv3]] - hGAL-9 C-terminal CRD + polysaccharide<br />
-
**[[2d6k]], [[2d6l]] – mGAL-9 CRD<br />
+
**[[2eal]] - mGAL-9 N-terminal CRD + pentasaccharide<br />
-
**[[2d6m]] – mGAL-9 CRD + lactose<br />
+
**[[2d6k]], [[2d6l]] – mGAL-9 N-terminal CRD<br />
-
**[[2d6n]], [[2d6o]]– mGAL-9 CRD + acetyllactosamine<br />
+
**[[2d6m]] – mGAL-9 N-terminal CRD + lactose<br />
-
**[[2d6p]] – mGAL-9 CRD + antigen<br />
+
**[[2d6n]], [[2d6o]]– mGAL-9 N-terminal CRD + acetyllactosamine<br />
 +
**[[2d6p]] – mGAL-9 N-terminal CRD + antigen<br />
-
*Galectin-10
+
*Galectin-10; Residues 1-142
**[[5xrg]], [[5xrh]], [[6gks]], [[6gkq]] – hGAL-10 <br />
**[[5xrg]], [[5xrh]], [[6gks]], [[6gkq]] – hGAL-10 <br />
Line 141: Line 148:
**[[5y03]], [[5xg9]], [[6a65]], [[6a66]], [[5xg8]], [[6kjw]], [[6kjx]], [[6kjy]] – hGAL-13 (mutant)<br />
**[[5y03]], [[5xg9]], [[6a65]], [[6a66]], [[5xg8]], [[6kjw]], [[6kjx]], [[6kjy]] – hGAL-13 (mutant)<br />
**[[6a62]], [[6a63]], [[6a64]] – hGAL-13 (mutant) + lactose<br />
**[[6a62]], [[6a63]], [[6a64]] – hGAL-13 (mutant) + lactose<br />
 +
**[[7cyb]] – smGAL-13 – squirrel monkey<br />
 +
**[[7cya]] – smGAL-13 + lactose <br />
*Galectin-14
*Galectin-14
Line 146: Line 155:
**[[6k2y]] – hGAL-14 <br />
**[[6k2y]] – hGAL-14 <br />
**[[6k2z]] – hGAL-14 + lactose<br />
**[[6k2z]] – hGAL-14 + lactose<br />
 +
 +
*Galectin-16
 +
 +
**[[6ljp]] – hGAL-16 <br />
 +
**[[6ljq]], [[6ljr]] – hGAL-16 (mutant) + lactose<br />
*Galectin
*Galectin

Revision as of 10:22, 3 August 2021

3D structures of galectin

Updated on 03-August-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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