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1ij9
From Proteopedia
(Difference between revisions)
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<StructureSection load='1ij9' size='340' side='right'caption='[[1ij9]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='1ij9' size='340' side='right'caption='[[1ij9]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1ij9]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1ij9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IJ9 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ij9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ij9 OCA], [https://pdbe.org/1ij9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ij9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ij9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ij9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VCAM1_HUMAN VCAM1_HUMAN]] Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 11:01, 4 August 2021
Highly Hydrated Human VCAM-1 Fragment
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