1jw3

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<StructureSection load='1jw3' size='340' side='right'caption='[[1jw3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='1jw3' size='340' side='right'caption='[[1jw3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1jw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JW3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1jw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JW3 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw3 OCA], [http://pdbe.org/1jw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jw3 RCSB], [http://www.ebi.ac.uk/pdbsum/1jw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jw3 ProSAT], [http://www.topsan.org/Proteins/NESGC/1jw3 TOPSAN]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw3 OCA], [https://pdbe.org/1jw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jw3 RCSB], [https://www.ebi.ac.uk/pdbsum/1jw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jw3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1jw3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARCH_METTH ARCH_METTH]] Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). May also act as a chaperone or modulator of proteins involved in DNA or RNA processing.
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[[https://www.uniprot.org/uniprot/ARCH_METTH ARCH_METTH]] Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). May also act as a chaperone or modulator of proteins involved in DNA or RNA processing.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:46, 11 August 2021

Solution Structure of Methanobacterium Thermoautotrophicum Protein 1598. Ontario Centre for Structural Proteomics target MTH1598_1_140; Northeast Structural Genomics Target TT6

PDB ID 1jw3

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