Heat Shock Protein structures

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Revision as of 08:12, 24 August 2021

3D Structures of Heat Shock Proteins

Updated on 24-August-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/Heat_Shock_Protein_structures"

Category: Topic Page

@@ Line 123: / Line 123: @@
 **[[4io8]], [[5aqw]], [[5aqx]], [[5aqy]], [[5aqz]], [[5ar0]], [[5mkr]], [[5mks]] - hHsp70 NBD + inhibitor<br />
 **[[6b1i]] - hHsp70 NBD + ADP<br />
-**[[6b1n]] - hHsp70 NBD (mutant) + ADP<br />
+**[[6b1n]], [[6zyi]] - hHsp70 NBD (mutant) + ADP<br />
 **[[6b1m]] - hHsp70 NBD (mutant) + ANP<br />
 **[[2e8a]] - hHsp70 NBD+AMPPNP<br />
@@ Line 142: / Line 142: @@
 **[[3gl1]] - ScHsp70 NBD – ''Saccharomyces cerevisiae''<br />
 **[[2d2e]], [[3d2f]] – ScHsp70 NBD+SSE1(Hsp110)<br />
+**[[3lca]] – yHsp70 Ssa1 CT+yTOM71<br />
 **[[2v7y]] – Hsp70 NBD+SBD – ''Geobacillus kaustophilus''<br />
 **[[3l6q]] - CpHsp70 NBD – ''Cryptosporidium parvum''<br />
 **[[3kvg]] - CpHsp70 NBD+AMPPNP<br />
 **[[3l4i]] - CpHsp70 NBD+ADP+P<br />
-**[[6rzy]] – PfHsp70 residues 81-148  – ''Plasmodium falciparum''<br />
 **[[6rzq]] – PfHsp70 NTD+ANP <br />
 **[[6s02]] – PfHsp70 NTD+ADP <br />
+**[[7ooe]], [[7oog]], [[7ooh]], [[7p31]] – PfHsp70 NTD+AMP derivative + inhibitor <br />
+**[[6zhi]] - PfHsp70 CT + peptide<br />
 *Hsp70 family protein 5 or endoplasmic reticulum chaperone BIP
@@ Line 156: / Line 158: @@
 **[[6h9u]], [[6ha7]] - haBIP + mesencephalic atrocyte-derived neurotrophic factor - hamster <br />
-*DnaK (Hsp70 from ''E. coli'') Domains: NBD 1-383; SBD 389-607
+*DnaK or chaperone protein DnaK (Hsp70 from ''E. coli'') Domains: NBD 1-383; SBD 389-607
 **[[4b9q]] - EcDnaK NBD + SBD + ATP<br />
@@ Line 169: / Line 171: @@
 **[[1bpr]], [[1dg4]], [[2bpr]] - EcDnaK SBD – NMR<br />
 **[[1q5l]] - EcDnaK SBD + peptide – NMR<br />
-**[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]] – EcDnaK SBD + peptide<br />
+**[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]], [[7jmm]], [[7jn8]], [[7jn9]], [[7jne]], [[7n6j]], [[7n6k]], [[7n6l]], [[7n6m]] – EcDnaK SBD + peptide<br />
+**[[7kzi]], [[7kzu]] – EcDnaK/peptide<br />
 **[[1q5l]] - EcDnaK SBD +peptide – NMR<br />
 **[[4r5g]] - EcDnaK CT + inhibitor<br />
-**[[4rtf]] DnaK + ATP – ''Mycobacterium tuberculosis''<br />
+**[[4rtf]] - MtDnaK + ATP – ''Mycobacterium tuberculosis''<br />
+**[[6w6e]] - MtDnaK NBD + ClpB + ADP<br />
+**[[7l6n]] - MtDnaK NBD + ClpB + ADP – Cryo EM<br />
 **[[5obx]] - MgDnaK NBD – ''Mycoplasma genitalium''<br />
 **[[5obv]], [[5obu]] - MgDnaK NBD (mutant) <br />
@@ Line 178: / Line 183: @@
 **[[5obw]] - MgDnaK NBD + ATP <br />
-*Hsp75
+*Hsp75 or TRAP-1
 **[[5f3k]], [[5f5r]] – hHsp75 NTD<br />
 **[[5hph]] – hHsp75 residues 60-554<br />
-**[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]] – hHsp75 + inhibitor<br />
+**[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]], [[7c7b]], [[7c7c]] – hHsp75 + inhibitor<br />
 *Hsp83
@@ Line 204: / Line 209: @@
 **[[6gqr]], [[3t0z]], [[3t2s]], [[3t10]], [[3t1k]], [[6gq6]], [[6gpy]], [[6gpt]], [[6gpr]], [[1byq]] - hHsp90-α NTD + nucleotide<br />
 **[[6gr5]], [[6gr3]], [[6gr1]], [[6gqu]], [[6gqs]], [[6gpp]], [[6gpo]], [[6gph]], [[6gpf]], [[6gp8]] - hHsp90-α NTD (mutant) + nucleotide<br />
-**[[6gjh]] - hHsp90 NTD+ peptide<br />
 **[[3k97]], [[3hek]], [[3mnq]] – hHsp90 NTD+pyrrolidin derivative <br />
-**[[3k98]], [[3k99]], [[3qtf]], [[5lo5]] - hHsp90 NTD+indole derivative<br />
+**[[3k98]], [[3k99]], [[3qtf]], [[5lo5]], [[7lsz]], [[7lt0]] - hHsp90 NTD+indole derivative<br />
 **[[3r91]] - hHsp90 NTD (mutant) +indole derivative<br />
 **[[3hhu]], [[4jql]] - hHsp90 NTD+ carbamic acid derivative<br />
@@ Line 222: / Line 226: @@
 **[[2qg0]], [[2bz5]] - hHsp90 NTD+sulfonamide derivative<br />
 **[[2yi0]], [[2yi5]], [[2yi6]], [[2yi7]], [[5fnd]] - hHsp90 NTD + thiadiazole derivative<br />
-**[[4hy6]], [[6ey8]], [[6ey9]], [[6eya]], [[6eyb]], [[5odx]], [[5oci]], [[5nyh]], [[5lny]], [[5lnz]], [[5lo0]], [[5lo1]], [[5lo6]] - hHsp90 NTD + indazole derivative<br />
+**[[4hy6]], [[6ey8]], [[6ey9]], [[6eya]], [[6eyb]], [[5odx]], [[5oci]], [[5nyh]], [[5lny]], [[5lnz]], [[5lo0]], [[5lo1]], [[5lo6]], [[6lti]], [[6ltk]] - hHsp90 NTD + indazole derivative<br />
 **[[5nyi]] - hHsp90 NTD + resorcinol derivative<br />
 **[[2qg2]], [[2cvi]], [[2cvj]], [[2uwd]], [[4b7p]] - hHsp90 NTD+oxazole derivative<br />
@@ Line 228: / Line 232: @@
 **[[3inw]], [[3inx]] - hHsp90 NTD+pochoxime derivative<br />
 **[[2ccs]], [[2cct]], [[2ccu]], [[2byh]], [[2byi]], [[2bsm]], [[2bt0]], [[1yc3]], [[1yc1]], [[1yc4]], [[6eln]], [[6elo]], [[6elp]], [[6fcj]], [[5zr3]], [[5zrd]] - hHsp90 NTD+pyrazol derivative<br />
-**[[2ye2]], [[2ye3]], [[2ye4]], [[2ye5]], [[2ye6]], [[2ye7]], [[2ye8]], [[2ye9]], [[2yea]], [[2yeb]], [[2yec]], [[2yed]], [[2yee]], [[2yef]], [[2yeg]], [[2yeh]], [[2yei]], [[2yej]], [[2yjw]], [[2yjx]], [[2yk2]], [[2yk9]], [[2ykb]], [[2ykc]], [[2yke]], [[2yki]], [[2ykj]], [[3ow6]], [[3owb]], [[3owd]], [[3qdd]], [[3tuh]], [[3vha]], [[3vhc]], [[3vhd]], [[4awo]], [[4awp]], [[4awq]], [[4eeh]], [[4eft]], [[4efu]], [[4egh]], [[4egi]], [[4egk]], [[4fcp]], [[4fcq]], [[4fcr]], [[3wha]], [[4bqg]], [[4bqj]], [[4l8z]], [[4l90]], [[4l91]], [[4l93]], [[4lwe]], [[4l94]], [[4lwf]], [[4lwg]], [[4lwh]], [[4lwi]], [[4nh7]], [[4nh8]], [[4nh9]], [[4o09]], [[4o0b]], [[4r3m]], [[4u93]], [[4w7t]], [[4xip]], [[4xiq]], [[4xir]], [[4xit]], [[4ykq]], [[4ykr]], [[4ykt]], [[4yku]], [[4ykw]], [[4ykx]], [[4yky]], [[4ykz]], [[5cf0]], [[5fnf]], [[5ggz]], [[5m4e]], [[5m4h]], [[6ceo]], [[5vyy]], [[5t21]], [[5lq9]], [[5lr1]], [[5lr7]], [[5lrl]], [[5lrz]], [[5ls1]], [[5h22]], [[6hhr]], [[6u98]], [[6u99]], [[6u9a]], [[6u9b]] - hHsp90 NTD + inhibitor<br />
+**[[2ye2]], [[2ye3]], [[2ye4]], [[2ye5]], [[2ye6]], [[2ye7]], [[2ye8]], [[2ye9]], [[2yea]], [[2yeb]], [[2yec]], [[2yed]], [[2yee]], [[2yef]], [[2yeg]], [[2yeh]], [[2yei]], [[2yej]], [[2yjw]], [[2yjx]], [[2yk2]], [[2yk9]], [[2ykb]], [[2ykc]], [[2yke]], [[2yki]], [[2ykj]], [[3ow6]], [[3owb]], [[3owd]], [[3qdd]], [[3tuh]], [[3vha]], [[3vhc]], [[3vhd]], [[4awo]], [[4awp]], [[4awq]], [[4eeh]], [[4eft]], [[4efu]], [[4egh]], [[4egi]], [[4egk]], [[4fcp]], [[4fcq]], [[4fcr]], [[3wha]], [[4bqg]], [[4bqj]], [[4l8z]], [[4l90]], [[4l91]], [[4l93]], [[4lwe]], [[4l94]], [[4lwf]], [[4lwg]], [[4lwh]], [[4lwi]], [[4nh7]], [[4nh8]], [[4nh9]], [[4o09]], [[4o0b]], [[4r3m]], [[4u93]], [[4w7t]], [[4xip]], [[4xiq]], [[4xir]], [[4xit]], [[4ykq]], [[4ykr]], [[4ykt]], [[4yku]], [[4ykw]], [[4ykx]], [[4yky]], [[4ykz]], [[5cf0]], [[5fnf]], [[5ggz]], [[5m4e]], [[5m4h]], [[6ceo]], [[5vyy]], [[5t21]], [[5lq9]], [[5lr1]], [[5lr7]], [[5lrl]], [[5lrz]], [[5ls1]], [[5h22]], [[6hhr]], [[6lr9]], [[6lt8]], [[6tn4]], [[6tn5]], [[6u98]], [[6u99]], [[6u9a]], [[6u9b]] - hHsp90 NTD + inhibitor<br />
 **[[2xhr]], [[2xht]], [[2xhx]], [[2xjg]], [[2xjj]], [[2xjx]], [[2xk2]], [[2xdx]], [[2xdu]], [[2xds]], [[2xdl]], [[2xdk]], [[2xab]], [[2vcj]], [[2vci]], [[3hyy]], [[3hyz]], [[3hz1]], [[3hz5]], [[3mnr]], [[2af6]] - hHsp90 NTD+ antigen<br />
-**[[1osf]], [[1yer]], [[1yes]], [[1yet]] - hHsp90 NTD+geldamycin <br />
+**[[1osf]], [[1yer]], [[1yes]], [[1yet]], [[6lsz]] - hHsp90 NTD+ drug <br />
-**[[2hg1]], [[2gfd]], [[2fyp]], [[2exl]], [[1u0z]], [[1qy8]], [[1ysz]], [[1u2o]], [[6d28]], [[6d1x]], [[1qye]], [[3o2f]] - dHsp90B1 NTD+ligand<br />
+**[[2hg1]], [[2gfd]], [[2fyp]], [[2exl]], [[1u0z]], [[1qy8]], [[1ysz]], [[1u2o]], [[6d28]], [[6d1x]], [[1qye]], [[3o2f]], [[6d1x]], [[6d28]]  - dHsp90B1 NTD+ligand<br />
 **[[2esa]] - dHsp90B1 NTD (mutant) +ligand<br />
 **[[1yt0]], [[1tc6]], [[1tba]], [[1tc0]] - dHsp90B1 NTD+ nucleotide<br />
+**[[5wmt]], [[6aol]], [[6aom]], [[6asq]], [[6baw]], [[6c91]], [[6cyi]] - dHsp90B1 NTD+ inhibitor<br />
+**[[6asp]] - dHsp90B1 NTD + drug <br />
+**[[7d1v]], [[7d22]], [[7d24]], [[7d25]], [[7d26]] - mHsp90-a NTD + inhibitor - mouse<br />
 **[[2jki]] - baHsp90 NTD+SGT1 domain protein – barley<br />
 **[[2xcm]] – baHsp90 NTD+CGT1+RAR1 <br />
@@ Line 241: / Line 248: @@
 **[[3ied]] - PfHsp90 NTD+ANP <br />
 **[[3k60]] - PfHsp90 NTD+ADP<br />
+**[[6cji]] – CaHsp90 NTD – ''Candida albicans''<br />
+**[[6cjl]], [[6cjp]] – CaHsp90 NTD + radicicol<br />
+**[[6cjj]] – CaHsp90 NTD + ADP<br />
+**[[6cjr]], [[6cjs]] – CaHsp90 NTD + inhibitor<br />
+**[[7k9s]], [[7k9u]], [[7k9v]], [[7k9w]] – CnHsp90 NTD + inhibitor<br />
 *''Hsp90-α MD''
@@ Line 262: / Line 274: @@
 *''Hsp90-α full length''
+**[[6xg6]] - hHsp90 + ADP – Cryo EM <br />
 **[[2qf6]] - hHsp90 + antigen<br />
 **[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br />
@@ Line 299: / Line 312: @@
 **[[3fp2]] – yHsp82 CT+TOM71
-* Hsp100 are named ClpA or ClpB
+* Hsp100 are named ClpA or ClpB or ClpC or ClpL or ClpP
 **[[1r6b]], [[1ksf]] – EcClpA (mutant) <br />
@@ Line 305: / Line 318: @@
 **[[1r6o]], [[1r6q]] – EcClpA N-terminal + ClpS<br />
 **[[1mg9]], [[1lzw]], [[1mbu]], [[1mbv]], [[1mbx]] – EcClpA + YLJA<br />
+**[[6w1z]], [[6w20]], [[6w21]], [[6w22]], [[6w23]], [[6w24]] – EcClpA + RepA + GFP + ADP + ATP – Cryo EM<br />
+**[[6uqe]], [[6uqo]] – EcClpA + ClpP + RepA + GFP + ADP + ATPgS – Cryo EM<br />
 **[[4ciu]] - EcClpB (mutant)<br />
 **[[4d2u]], [[4d2x]], [[4d2q]] - EcClpB – Cryo EM<br />
 **[[5og1]], [[5ofo]] - EcClpB + ATPgS – Cryo EM<br />
-**[[6qs8]], [[6qs7]], [[6qs6]], [[6og3]] - EcClpB + casein – Cryo EM<br />
+**[[6qs8]], [[6qs7]], [[6qs6]], [[6og3]] - EcClpB (mutant) + casein – Cryo EM<br />
+**[[6og2]] - EcClpB (mutant) + ADP – Cryo EM<br />
+**[[6og1]] - EcClpB (mutant) + ADP + ATPgS – Cryo EM<br />
+**[[6qs4]] - EcClpB + casein + ADP + ATPgS – Cryo EM<br />
+**[[6rn4]] - EcClpB (mutant) + casein + ATPgS – Cryo EM<br />
+**[[6oax]], [[6oay]] - EcClpB (mutant) + casein + ADP + ATPgS – Cryo EM<br />
 **[[1khy]] – EcClpB NTD <br />
 **[[1jbk]] – EcClpB nucleotide binding domain 1<br />
@@ Line 324: / Line 344: @@
 **[[3zri]] - VcClpB NTD – ''Vibrio cholerae''<br />
 **[[3zrj]] - VcClpB NTD + peptide<br />
+**[[6ed3]] - MtClpB – Cryo EM<br />
+**[[6w6e]] - MtClpB + ADP + ATPgS – Cryo EM<br />
+**[[6dju]], [[6djv]] - MtClpB + casein + ATPgS – Cryo EM<br />
+**[[6em8]], [[6em9]] - SaClpC – Cryo EM<br />
+**[[6emw]] - SaClpC + MecA – Cryo EM<br />
+**[[6pba]], [[6pbq]] - MtClpC NTD <br />
+**[[6pbs]] - MtClpC NTD + ecumicin<br />
+**[[6cn8]] - MtClpC NTD + rufomycin<br />
+**[[6lsy]] - SpClpL – Cryo EM<br />
+**[[6lt4]] - SpClpL + ATPgS – Cryo EM<br />
+**[[7m1l]], [[7m1m]] – ClpP2 – ''Pseudomonas aeruginosa''<br />
+**[[6cfd]] – ClpP + antibiotic – ''Enterococcus faecium''<br />
 *Hsp101

Heat Shock Protein structures

From Proteopedia

Revision as of 08:12, 24 August 2021

3D Structures of Heat Shock Proteins

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