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6nt3
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==Cryo-EM structure of a human-cockroach hybrid Nav channel.== | ==Cryo-EM structure of a human-cockroach hybrid Nav channel.== | ||
| - | < | + | <SX load='6nt3' size='340' side='right' viewer='molstar' caption='[[6nt3]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6nt3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NT3 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6nt3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/American_cockroach American cockroach]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NT3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=76F:(7E,21R,24S)-27-amino-24-hydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaheptacos-7-en-21-yl+(9Z,12E)-octadeca-9,12-dienoate'>76F</scene>, <scene name='pdbligand=AJP:Digitonin'>AJP</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCN9A, NENA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6978 American cockroach])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nt3 OCA], [https://pdbe.org/6nt3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nt3 RCSB], [https://www.ebi.ac.uk/pdbsum/6nt3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nt3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SCNA1_PERAM SCNA1_PERAM]] Mediates the voltage-dependent sodium ion permeability of excitable membranes.[RuleBase:RU361132]<ref>PMID:28183995</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
| + | [[Category: American cockroach]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Clairfeuille, T]] | [[Category: Clairfeuille, T]] | ||
[[Category: Payandeh, J]] | [[Category: Payandeh, J]] | ||
Current revision
Cryo-EM structure of a human-cockroach hybrid Nav channel.
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