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1rl5
From Proteopedia
(Difference between revisions)
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<StructureSection load='1rl5' size='340' side='right'caption='[[1rl5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1rl5' size='340' side='right'caption='[[1rl5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1rl5]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1rl5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RL5 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl5 OCA], [https://pdbe.org/1rl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rl5 RCSB], [https://www.ebi.ac.uk/pdbsum/1rl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rl5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CX1_NAJOX CX1_NAJOX]] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type). CTI interacts with membrane weaker than CTII. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:14, 15 September 2021
NMR structure with tightly bound water molecule of cytotoxin I from Naja oxiana in aqueous solution (major form)
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