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Hydroxylases 3D structures

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Line 14: Line 14:
**[[1j8u]] - hPAH catalytic domain + cofactor<br />
**[[1j8u]] - hPAH catalytic domain + cofactor<br />
**[[1dmw]] - hPAH catalytic domain + cofactor<br />
**[[1dmw]] - hPAH catalytic domain + cofactor<br />
-
**[[6hpo]] - hPAH catalytic domain + cofactor + Fe<br />
 
**[[1tg2]], [[1lrm]] - hPAH catalytic domain (mutant) + cofactor<br />
**[[1tg2]], [[1lrm]] - hPAH catalytic domain (mutant) + cofactor<br />
**[[1mmk]], [[1mmt]], [[1kw0]] - hPAH catalytic domain + cofactor + substrate<br />
**[[1mmk]], [[1mmt]], [[1kw0]] - hPAH catalytic domain + cofactor + substrate<br />
Line 39: Line 38:
**[[2xsn]] – hTH catalytic domain <br />
**[[2xsn]] – hTH catalytic domain <br />
-
**[2toh]], [[1toh]] – TH catalytic and tetramerization domains - rat
+
**[2toh]], [[1toh]] – TH catalytic and tetramerization domains - rat<br />
 +
**[[7kqr]], [[7kqs]], [[7kqt]], [[7kqu]] – TH + heme + Tyr derivative – ''Streptomyces sclerotialus'' <br />
*Tryptophan hydroxylase
*Tryptophan hydroxylase
Line 60: Line 60:
**[[1pdh]] – PfPHBH + FAD derivative + PHB <br />
**[[1pdh]] – PfPHBH + FAD derivative + PHB <br />
**[[1cj2]], [[1cj3]], [[1cj4]] – PfPHBH (mutant) + FAD derivative + PHB <br />
**[[1cj2]], [[1cj3]], [[1cj4]] – PfPHBH (mutant) + FAD derivative + PHB <br />
-
**[[1dod]], [[1doe]] – PaPHBH + FAD + 2,4-DHB <br />
+
**[[1dob]], [[1doc]], [[1pxa]], [[1pxb]], [[1pxc]] – PaPHBH + FAD + PHB – ''Pseudomonas aeruginosa''<br />
 +
**[[1dod]], [[1doe]], [[1iuv]], [[1iuw]], [[1iux]] – PaPHBH + FAD + DHB derivative <br />
**[[1ius]], [[1iut]], [[1iuu]] – PaPHBH + FAD + 4-aminobenzoate <br />
**[[1ius]], [[1iut]], [[1iuu]] – PaPHBH + FAD + 4-aminobenzoate <br />
-
**[[1iuv]], [[1iuw]], [[1iux]] – PaPHBH + FAD + 4,4-DHB <br />
+
**[[6ju1]] – PaPHBH (mutant) + FAD + DHB derivative <br />
**[[1d7l]] – PaPHBH + FAD derivative + PHB <br />
**[[1d7l]] – PaPHBH + FAD derivative + PHB <br />
**[[1k0i]], [[1ykj]] – PaPHBH (mutant) + FAD + PHB <br />
**[[1k0i]], [[1ykj]] – PaPHBH (mutant) + FAD + PHB <br />
**[[1k0j]] – PaPHBH (mutant) + FAD + NADPH <br />
**[[1k0j]] – PaPHBH (mutant) + FAD + NADPH <br />
**[[1k0l]] – PaPHBH (mutant) + FAD <br />
**[[1k0l]] – PaPHBH (mutant) + FAD <br />
-
**[[6dll]] – PfPHBH + FAD – ''Pseudomonas putida''<br />
+
**[[5tti]], [[6dll]] – PfPHBH + FAD – ''Pseudomonas putida''<br />
**[[2dki]] – CtPHBH + FAD – ''Comamonas testosteroni''<br />
**[[2dki]] – CtPHBH + FAD – ''Comamonas testosteroni''<br />
**[[2dkh]] – CtPHBH + FAD + hydroxy-benzoate <br />
**[[2dkh]] – CtPHBH + FAD + hydroxy-benzoate <br />
-
*Apartyl/asparaginyl β-hydroxylase
+
*Apartyl/asparaginyl β-hydroxylase; Domain – oxygenase and TPR 301-758
-
**[[6qa5]] – hAAH oxygenase and TPR domain 301-758<br />
+
**[[6qa5]] – hAAH oxygenase and TPR domain<br />
**[[5jz6]] – hAAH oxygenase and TPR domain + malate + Mn <br />
**[[5jz6]] – hAAH oxygenase and TPR domain + malate + Mn <br />
**[[5apa]] – hAAH residues 562-758 + malate + Ni <br />
**[[5apa]] – hAAH residues 562-758 + malate + Ni <br />
**[[5jza]] – hAAH oxygenase and TPR domain + oxalylglycine + Mn <br />
**[[5jza]] – hAAH oxygenase and TPR domain + oxalylglycine + Mn <br />
-
**[[5jz8]], [[5jzu]], [[6rk9]], [[5jqy]] – hAAH oxygenase and TPR domain + oxalylglycine + Mn + coagulation factor X peptide<br />
+
**[[6yyu]], [[6yyv]] – hAAH oxygenase and TPR domain + oxoglutarate + Mn <br />
 +
**[[6yyw]], [[6yyx]], [[6yyy]], [[6z6q]] – hAAH oxygenase and TPR domain + oxoglutarate + Mn + coagulation factor X peptide<br />
 +
**[[5jz8]], [[5jzu]], [[6rk9]], [[5jqy]], [[6rk9]], [[6z6r]] – hAAH oxygenase and TPR domain + oxalyl derivative + Mn + coagulation factor X peptide<br />
 +
**[[7e6j]] – hAAH oxygenase and TPR domain (mutant) + coagulation factor X peptide<br />
**[[6q9f]], [[6q9i]] – hAAH oxygenase and TPR domain (mutant) + oxalylglycine + Mn + coagulation factor X peptide<br />
**[[6q9f]], [[6q9i]] – hAAH oxygenase and TPR domain (mutant) + oxalylglycine + Mn + coagulation factor X peptide<br />
-
**[[5jtc]] – hAAH oxygenase and TPR domain + pyridine dicarboxylate + Mn + coagulation factor X peptide<br />
+
**[[5jtc]], [[7bmi]], [[7bmj]] – hAAH oxygenase and TPR domain + pyridine dicarboxylate + Mn + coagulation factor X peptide<br />
*Alpha-ketoglutarate-dependent L-arginine hydroxylase
*Alpha-ketoglutarate-dependent L-arginine hydroxylase

Revision as of 09:37, 29 September 2021

3D structures of hydroxylases

Updated on 29-September-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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