1v5b

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<StructureSection load='1v5b' size='340' side='right'caption='[[1v5b]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<StructureSection load='1v5b' size='340' side='right'caption='[[1v5b]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_7050 Atcc 7050]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V5B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_7050 Atcc 7050]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [http://pdbe.org/1v5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [http://www.ebi.ac.uk/pdbsum/1v5b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [https://pdbe.org/1v5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [https://www.ebi.ac.uk/pdbsum/1v5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEU3_BACCO LEU3_BACCO]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
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[[https://www.uniprot.org/uniprot/LEU3_BACCO LEU3_BACCO]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:25, 6 October 2021

The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans

PDB ID 1v5b

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