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Janus kinase 3D structures
From Proteopedia
(Difference between revisions)
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*''JAK1 kinase or JH1 domain residues 869-1153'' | *''JAK1 kinase or JH1 domain residues 869-1153'' | ||
| - | **[[4e4l]], [[4e4n]], [[4e5w]], [[4ehz]], [[4ei4]], [[4fk6]], [[4i5c]], [[4k6z]], [[3eyg]], [[3eyh]], [[5e1e]], [[5hx8]], [[5khx]], [[6n77]], [[6n78]], [[6n79]], [[6n7a]], [[6n7b]], [[6n7c]], [[6n7d]], [[6elr]], [[6dbn]], [[4k77]], [[6bbu]], [[5wo4]], [[6w8l]], [[6hzu]], [[6rsb]], [[6rsc]], [[6rsd]], [[6rse]], [[6rsh]], [[6sm8]], [[6smb]], [[6tpe]], [[6tpf]] - hJAK1 kinase domain + PTyr + inhibitor - human<br /> | + | **[[4e4l]], [[4e4n]], [[4e5w]], [[4ehz]], [[4ei4]], [[4fk6]], [[4i5c]], [[4k6z]], [[3eyg]], [[3eyh]], [[5e1e]], [[5hx8]], [[5khx]], [[6n77]], [[6n78]], [[6n79]], [[6n7a]], [[6n7b]], [[6n7c]], [[6n7d]], [[6elr]], [[6dbn]], [[4k77]], [[6bbu]], [[5wo4]], [[6w8l]], [[6hzu]], [[6rsb]], [[6rsc]], [[6rsd]], [[6rse]], [[6rsh]], [[6sm8]], [[6smb]], [[6tpe]], [[6tpf]], [[6vnb]], [[6vnc]], [[6vne]], [[6vnf]], [[6vng]], [[6vnh]], [[6vni]], [[6vnj]], [[6vnk]], [[6vnl]], [[6vnm]], [[6vs3]], [[6vsn]], [[6wtq]] - hJAK1 kinase domain + PTyr + inhibitor - human<br /> |
**[[5khw]] – hJAK1 kinase domain + PTyr + ADP<br /> | **[[5khw]] – hJAK1 kinase domain + PTyr + ADP<br /> | ||
**[[6c7y]]]] – hJAK1 kinase domain + PTyr + SOCY1 + ADP<br /> | **[[6c7y]]]] – hJAK1 kinase domain + PTyr + SOCY1 + ADP<br /> | ||
| - | **[[6aah]] – hJAK1 kinase domain + PTyr + drug <br /> | + | **[[6aah]], [[6aaj]], [[6vgl]], [[6vn8]], [[6wtn]], [[6wto]] – hJAK1 kinase domain + PTyr + drug <br /> |
*''JAK1 pseudokinase domain residues 561-860'' | *''JAK1 pseudokinase domain residues 561-860'' | ||
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**[[4fvp]] - hJAK2 kinase domain <br /> | **[[4fvp]] - hJAK2 kinase domain <br /> | ||
**[[3ugc]], [[4bbe]], [[4bbf]], [[3zmm]], [[2xa4]], [[4c61]], [[4c62]], [[5l3a]], [[5tq3]], [[5tq4]], [[5tq5]], [[5tq6]], [[5tq7]], [[5tq8]], [[6tpd]] – hJAK2 kinase domain (mutant) + inhibitor <br /> | **[[3ugc]], [[4bbe]], [[4bbf]], [[3zmm]], [[2xa4]], [[4c61]], [[4c62]], [[5l3a]], [[5tq3]], [[5tq4]], [[5tq5]], [[5tq6]], [[5tq7]], [[5tq8]], [[6tpd]] – hJAK2 kinase domain (mutant) + inhibitor <br /> | ||
| - | **[[3e62]], [[3e63]], [[3e64]], [[2w1i]], [[4ytc]], [[4ytf]], [[4yth]], [[4yti]], [[4zim]], [[5aep]], [[5cf4]], [[5cf5]], [[5cf6]], [[3io7]], [[3iok]], [[3kck]], [[3jy9]], [[3lpb]], [[3krr]], [[3q32]], [[3tjc]], [[3tjd]], [[3rvg]], [[4aqc]], [[4e4m]], [[4f09]], [[4hge]], [[4d0w]], [[4d0x]], [[4d1s]], [[4p7e]], [[4aep]], [[5cf8]], [[6ggh]] – hJAK2 kinase domain + PTyr + inhibitor <br /> | + | **[[3e62]], [[3e63]], [[3e64]], [[2w1i]], [[4ytc]], [[4ytf]], [[4yth]], [[4yti]], [[4zim]], [[5aep]], [[5cf4]], [[5cf5]], [[5cf6]], [[3io7]], [[3iok]], [[3kck]], [[3jy9]], [[3lpb]], [[3krr]], [[3q32]], [[3tjc]], [[3tjd]], [[3rvg]], [[4aqc]], [[4e4m]], [[4f09]], [[4hge]], [[4d0w]], [[4d0x]], [[4d1s]], [[4p7e]], [[4aep]], [[5cf8]], [[6ggh]], [[7ree]] – hJAK2 kinase domain + PTyr + inhibitor <br /> |
**[[2b7a]], [[3fup]], [[4e6d]], [[4e6q]], [[4f08]] – hJAK2 kinase domain (mutant) + PTyr + inhibitor <br /> | **[[2b7a]], [[3fup]], [[4e6d]], [[4e6q]], [[4f08]] – hJAK2 kinase domain (mutant) + PTyr + inhibitor <br /> | ||
**[[6aaj]] – hJAK2 kinase domain (mutant) + PTyr + drug <br /> | **[[6aaj]] – hJAK2 kinase domain (mutant) + PTyr + drug <br /> | ||
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**[[6obb]] - hJAK2 JH2 domain + inhibitor <br /> | **[[6obb]] - hJAK2 JH2 domain + inhibitor <br /> | ||
| - | **[[6brw]], [[6d2i]], [[6bs0]], [[6bss]], [[5wij]], [[5wik]], [[5wil]], [[5wim]], [[5win]], [[6g3c]], [[6m9h]], [[6oav]], [[6obf]], [[6obl]], [[6occ]] - hJAK2 JH2 domain (mutant) + inhibitor <br /> | + | **[[6brw]], [[6d2i]], [[6bs0]], [[6bss]], [[5wij]], [[5wik]], [[5wil]], [[5wim]], [[5win]], [[6g3c]], [[6m9h]], [[6oav]], [[6obf]], [[6obl]], [[6occ]], [[6x8e]], [[6xjk]], [[7jyo]], [[7jyq]] - hJAK2 JH2 domain (mutant) + inhibitor <br /> |
**[[3ugc]] – hJAK2 JH2 domain (mutant) <br /> | **[[3ugc]] – hJAK2 JH2 domain (mutant) <br /> | ||
**[[4fvq]], [[4fvr]], [[5i4n]] – hJAK2 JH2 domain (mutant) + ATP<br /> | **[[4fvq]], [[4fvr]], [[5i4n]] – hJAK2 JH2 domain (mutant) + ATP<br /> | ||
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**[[1yvj]] – hJAK3 kinase domain (mutant) + PTyr + staurosporine analog<br /> | **[[1yvj]] – hJAK3 kinase domain (mutant) + PTyr + staurosporine analog<br /> | ||
**[[3lxk]], [[3lxl]], [[5wfj]] – hJAK3 kinase domain (mutant) + PTyr + inhibitor <br /> | **[[3lxk]], [[3lxl]], [[5wfj]] – hJAK3 kinase domain (mutant) + PTyr + inhibitor <br /> | ||
| - | **[[3pjc]], [[4v0g]], [[4z16]], [[5lwm]], [[5lwn]], [[5toz]], [[6glb]], [[6gl9]], [[6gla]], [[6ny4]], [[6dud]], [[6da4]] – hJAK3 kinase domain + inhibitor <br /> | + | **[[3pjc]], [[4v0g]], [[4z16]], [[5lwm]], [[5lwn]], [[5toz]], [[6glb]], [[6gl9]], [[6gla]], [[6ny4]], [[6dud]], [[6da4]], [[7apf]], [[7apg]] – hJAK3 kinase domain + inhibitor <br /> |
**[[4hvd]], [[4hvg]], [[4hvh]], [[4hvi]], [[3zc6]], [[3zep]], [[4i6q]], [[4qps]], [[4rio]], [[4qt1]], [[5tts]], [[5ttu]], [[5ttv]], [[5vo6]], [[6db3]], [[6db4]] – hJAK3 kinase domain (mutant) + inhibitor <br /> | **[[4hvd]], [[4hvg]], [[4hvh]], [[4hvi]], [[3zc6]], [[3zep]], [[4i6q]], [[4qps]], [[4rio]], [[4qt1]], [[5tts]], [[5ttu]], [[5ttv]], [[5vo6]], [[6db3]], [[6db4]] – hJAK3 kinase domain (mutant) + inhibitor <br /> | ||
**[[5w86]], [[6hzv]] – hJAK3 kinase domain + PTyr + inhibitor <br /> | **[[5w86]], [[6hzv]] – hJAK3 kinase domain + PTyr + inhibitor <br /> | ||
Revision as of 08:46, 10 October 2021
3D Structures of Janus kinase
Updated on 10-October-2021
