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3ibw
From Proteopedia
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==Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A== | ==Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A== | ||
| - | <StructureSection load='3ibw' size='340' side='right' caption='[[3ibw]], [[Resolution|resolution]] 1.93Å' scene=''> | + | <StructureSection load='3ibw' size='340' side='right'caption='[[3ibw]], [[Resolution|resolution]] 1.93Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ibw]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ibw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_49652 Atcc 49652]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IBW FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CT1545, relA ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CT1545, relA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1097 ATCC 49652])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/GTP_diphosphokinase GTP diphosphokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.5 2.7.6.5] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ibw OCA], [https://pdbe.org/3ibw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ibw RCSB], [https://www.ebi.ac.uk/pdbsum/3ibw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ibw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/Q8KC80_CHLTE Q8KC80_CHLTE]] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity).[RuleBase:RU003847] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/3ibw_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/3ibw_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ibw ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Atcc 49652]] |
[[Category: GTP diphosphokinase]] | [[Category: GTP diphosphokinase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Acton, T B]] | [[Category: Acton, T B]] | ||
| - | [[Category: Ciccosanti,C]] | + | [[Category: Ciccosanti, C]] |
[[Category: Everett, J K]] | [[Category: Everett, J K]] | ||
| - | [[Category: Hunt,J F]] | + | [[Category: Hunt, J F]] |
| - | [[Category: Janjua,J]] | + | [[Category: Janjua, J]] |
[[Category: Montelione, G T]] | [[Category: Montelione, G T]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
| Line 35: | Line 37: | ||
[[Category: Seetharaman, J]] | [[Category: Seetharaman, J]] | ||
[[Category: Su, M]] | [[Category: Su, M]] | ||
| - | [[Category: Tong,L]] | + | [[Category: Tong, L]] |
[[Category: Vorobiev, S]] | [[Category: Vorobiev, S]] | ||
| - | [[Category: Wang,H]] | + | [[Category: Wang, H]] |
| - | [[Category: Xiao,R]] | + | [[Category: Xiao, R]] |
[[Category: Act domain]] | [[Category: Act domain]] | ||
[[Category: Ctr148a]] | [[Category: Ctr148a]] | ||
Current revision
Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A
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Categories: Atcc 49652 | GTP diphosphokinase | Large Structures | Acton, T B | Ciccosanti, C | Everett, J K | Hunt, J F | Janjua, J | Montelione, G T | Structural genomic | Nair, R | Rost, B | Seetharaman, J | Su, M | Tong, L | Vorobiev, S | Wang, H | Xiao, R | Act domain | Ctr148a | Gtp pyrophosphokinase | Kinase | Nesg | PSI, Protein structure initiative | Transferase
