This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3k5b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3k5b" [edit=sysop:move=sysop])
Current revision (12:21, 13 October 2021) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3k5b.png|left|200px]]
 
-
{{STRUCTURE_3k5b| PDB=3k5b | SCENE= }}
+
==Crystal structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase==
 +
<StructureSection load='3k5b' size='340' side='right'caption='[[3k5b]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3k5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K5B FirstGlance]. <br>
 +
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">55981248, TTHA1279 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8]), 55981245, atpE, TTHA1276, vatE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k5b OCA], [https://pdbe.org/3k5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k5b RCSB], [https://www.ebi.ac.uk/pdbsum/3k5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k5b ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/3k5b_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k5b ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Proton-translocating ATPases are ubiquitous protein complexes that couple ATP catalysis with proton translocation via a rotary catalytic mechanism. The peripheral stalks are essential components that counteract torque generated from proton translocation during ATP synthesis or from ATP hydrolysis during proton pumping. Despite their essential role, the peripheral stalks are the least conserved component of the complexes, differing substantially between subtypes in composition and stoichiometry. We have determined the crystal structure of the peripheral stalk of the A-type ATPase/synthase from Thermus thermophilus consisting of subunits E and G. The structure contains a heterodimeric right-handed coiled coil, a protein fold never observed before. We have fitted this structure into the 23 A resolution EM density of the intact A-ATPase complex, revealing the precise location of the peripheral stalk and new implications for the function and assembly of proton-translocating ATPases.
-
===Crystal structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase===
+
The structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase.,Lee LK, Stewart AG, Donohoe M, Bernal RA, Stock D Nat Struct Mol Biol. 2010 Mar;17(3):373-8. Epub 2010 Feb 21. PMID:20173764<ref>PMID:20173764</ref>
-
{{ABSTRACT_PUBMED_20173764}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
==About this Structure==
+
<div class="pdbe-citations 3k5b" style="background-color:#fffaf0;"></div>
-
[[3k5b]] is a 4 chain structure of [[ATP synthase]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5B OCA].
+
==See Also==
==See Also==
-
*[[ATP synthase|ATP synthase]]
+
*[[ATPase 3D structures|ATPase 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:020173764</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Thermus thermophilus]]
+
</StructureSection>
-
[[Category: Bernal, R A.]]
+
[[Category: Large Structures]]
-
[[Category: Donohoe, M.]]
+
[[Category: Thet8]]
-
[[Category: Lee, L K.]]
+
[[Category: Bernal, R A]]
-
[[Category: Stewart, A G.]]
+
[[Category: Donohoe, M]]
-
[[Category: Stock, D.]]
+
[[Category: Lee, L K]]
 +
[[Category: Stewart, A G]]
 +
[[Category: Stock, D]]
[[Category: A-type atpase/synthase]]
[[Category: A-type atpase/synthase]]
[[Category: Atp synthesis]]
[[Category: Atp synthesis]]

Current revision

Crystal structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase

PDB ID 3k5b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3k5b"
Personal tools