This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lw9
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Structure of a Cytoplasmic Domain of Salmonella InvA== | ==Structure of a Cytoplasmic Domain of Salmonella InvA== | ||
| - | <StructureSection load='3lw9' size='340' side='right' caption='[[3lw9]], [[Resolution|resolution]] 1.85Å' scene=''> | + | <StructureSection load='3lw9' size='340' side='right'caption='[[3lw9]], [[Resolution|resolution]] 1.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3lw9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3lw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LW9 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">invA, STM2896 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">invA, STM2896 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lw9 OCA], [https://pdbe.org/3lw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3lw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lw9 ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/INVA_SALTY INVA_SALTY]] Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/3lw9_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/3lw9_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lw9 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 23: | Line 26: | ||
A conserved domain in type III secretion links the cytoplasmic domain of InvA to elements of the basal body.,Lilic M, Quezada CM, Stebbins CE Acta Crystallogr D Biol Crystallogr. 2010 Jun;66(Pt 6):709-13. Epub 2010 May 15. PMID:20516623<ref>PMID:20516623</ref> | A conserved domain in type III secretion links the cytoplasmic domain of InvA to elements of the basal body.,Lilic M, Quezada CM, Stebbins CE Acta Crystallogr D Biol Crystallogr. 2010 Jun;66(Pt 6):709-13. Epub 2010 May 15. PMID:20516623<ref>PMID:20516623</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 3lw9" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bacillus typhimurium loeffler 1892]] |
| - | [[Category: Lilic, M | + | [[Category: Large Structures]] |
| - | [[Category: Quezada, C M | + | [[Category: Lilic, M]] |
| - | [[Category: Stebbins, C E | + | [[Category: Quezada, C M]] |
| + | [[Category: Stebbins, C E]] | ||
[[Category: Bacterial pathogenesis]] | [[Category: Bacterial pathogenesis]] | ||
[[Category: Cell inner membrane]] | [[Category: Cell inner membrane]] | ||
Current revision
Structure of a Cytoplasmic Domain of Salmonella InvA
| |||||||||||
