This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2k4w
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica== | ==The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica== | ||
| - | <StructureSection load='2k4w' size='340' side='right' caption='[[2k4w]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | + | <StructureSection load='2k4w' size='340' side='right'caption='[[2k4w]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k4w]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k4w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_choleraesuis_choleraesuis Salmonella choleraesuis choleraesuis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K4W FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sodC2 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sodC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119912 Salmonella choleraesuis choleraesuis])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k4w OCA], [https://pdbe.org/2k4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k4w RCSB], [https://www.ebi.ac.uk/pdbsum/2k4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k4w ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/Q704S6_SALET Q704S6_SALET]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000393] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/2k4w_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/2k4w_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k4w ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 31: | Line 32: | ||
==See Also== | ==See Also== | ||
| - | *[[Superoxide | + | *[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Salmonella choleraesuis choleraesuis]] | [[Category: Salmonella choleraesuis choleraesuis]] | ||
[[Category: Superoxide dismutase]] | [[Category: Superoxide dismutase]] | ||
| Line 45: | Line 47: | ||
[[Category: Sette, M]] | [[Category: Sette, M]] | ||
[[Category: Bioinorganic chemistry]] | [[Category: Bioinorganic chemistry]] | ||
| + | [[Category: Copper]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Metalloenzyme]] | [[Category: Metalloenzyme]] | ||
| Line 54: | Line 57: | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Structural proteomics in europe]] | [[Category: Structural proteomics in europe]] | ||
| + | [[Category: Zinc]] | ||
Current revision
The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica
| |||||||||||
Categories: Large Structures | Salmonella choleraesuis choleraesuis | Superoxide dismutase | Battistoni, A | Jimenez, B | Mori, M | Piccioli, M | SPINE, Structural Proteomics in Europe | Sette, M | Bioinorganic chemistry | Copper | Metal-binding | Metalloenzyme | National project on protein structural and functional analyse | Nppsfa | Oxidoreductase | Solution structure | Spine | Structural genomic | Structural proteomics in europe | Zinc
