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3d1n

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==Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter==
==Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter==
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<StructureSection load='3d1n' size='340' side='right' caption='[[3d1n]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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<StructureSection load='3d1n' size='340' side='right'caption='[[3d1n]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d1n]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D1N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d1n]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D1N FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oct|1oct]], [[1au7|1au7]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1oct|1oct]], [[1au7|1au7]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POU6F1, BRN5, MPOU, TCFB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POU6F1, BRN5, MPOU, TCFB1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d1n OCA], [http://pdbe.org/3d1n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d1n RCSB], [http://www.ebi.ac.uk/pdbsum/3d1n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d1n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d1n OCA], [https://pdbe.org/3d1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d1n RCSB], [https://www.ebi.ac.uk/pdbsum/3d1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d1n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PO6F1_HUMAN PO6F1_HUMAN]] Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
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[[https://www.uniprot.org/uniprot/PO6F1_HUMAN PO6F1_HUMAN]] Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/3d1n_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/3d1n_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Ha, S C]]
[[Category: Ha, S C]]
[[Category: Kim, S H]]
[[Category: Kim, S H]]

Current revision

Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter

PDB ID 3d1n

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