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3f8u
From Proteopedia
(Difference between revisions)
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==Tapasin/ERp57 heterodimer== | ==Tapasin/ERp57 heterodimer== | ||
| - | <StructureSection load='3f8u' size='340' side='right' caption='[[3f8u]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='3f8u' size='340' side='right'caption='[[3f8u]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3f8u]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3f8u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8U FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDIA3, ERP57, ERP60, GRP58 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDIA3, ERP57, ERP60, GRP58 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), TAPBP, NGS17, TAPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein_disulfide-isomerase Protein disulfide-isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.4.1 5.3.4.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8u OCA], [https://pdbe.org/3f8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8u RCSB], [https://www.ebi.ac.uk/pdbsum/3f8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8u ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TPSN_HUMAN TPSN_HUMAN]] Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).<ref>PMID:10636848</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Protein disulfide-isomerase]] | [[Category: Protein disulfide-isomerase]] | ||
[[Category: Dong, G]] | [[Category: Dong, G]] | ||
Revision as of 19:51, 20 October 2021
Tapasin/ERp57 heterodimer
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Categories: Human | Large Structures | Protein disulfide-isomerase | Dong, G | Reinisch, K M | Beta barrel | Endoplasmic reticulum | Glycoprotein | Ig-like domain | Immune system-isomerase complex | Immunoglobulin domain | Isomerase | Membrane | Microsome | Protein disulfide isomerase | Redox-active cente | Thioredoxin-like fold

