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3fsl
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3fsl is ON HOLD Authors: Malashkevich, V.N., Ng, B., Kirsch, J.F. Description: Crystal structure of tyrosine aminotransferase tripple mutant (P181Q...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of tyrosine aminotransferase tripple mutant (P181Q,R183G,A321K) from Escherichia coli at 2.35 A resolution== | |
| + | <StructureSection load='3fsl' size='340' side='right'caption='[[3fsl]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3fsl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FSL FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b4054, JW4014, tat, tyrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aromatic-amino-acid_transaminase Aromatic-amino-acid transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.57 2.6.1.57] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fsl OCA], [https://pdbe.org/3fsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fsl RCSB], [https://www.ebi.ac.uk/pdbsum/3fsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fsl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/3fsl_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fsl ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Aromatic-amino-acid transaminase]] | |
| + | [[Category: Ecoli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kirsch, J F]] | ||
| + | [[Category: Malashkevich, V N]] | ||
| + | [[Category: Ng, B]] | ||
| + | [[Category: Amino-acid biosynthesis]] | ||
| + | [[Category: Aminotransferase]] | ||
| + | [[Category: Aromatic amino acid biosynthesis]] | ||
| + | [[Category: Internal aldimine]] | ||
| + | [[Category: Pyridoxal phosphate]] | ||
| + | [[Category: Schiff base]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Tyrosine aminotransferase]] | ||
Current revision
Crystal structure of tyrosine aminotransferase tripple mutant (P181Q,R183G,A321K) from Escherichia coli at 2.35 A resolution
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