This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2j4y
From Proteopedia
| Line 3: | Line 3: | ||
<StructureSection load='2j4y' size='340' side='right'caption='[[2j4y]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='2j4y' size='340' side='right'caption='[[2j4y]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2j4y]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2j4y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J4Y FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1eds|1eds]], [[1edv|1edv]], [[1edw|1edw]], [[1edx|1edx]], [[1f88|1f88]], [[1fdf|1fdf]], [[1gzm|1gzm]], [[1hzx|1hzx]], [[1jfp|1jfp]], [[1l9h|1l9h]], [[1ln6|1ln6]], [[1n3m|1n3m]], [[1nzs|1nzs]], [[1ov0|1ov0]], [[1ov1|1ov1]], [[1u19|1u19]], [[1vqx|1vqx]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1eds|1eds]], [[1edv|1edv]], [[1edw|1edw]], [[1edx|1edx]], [[1f88|1f88]], [[1fdf|1fdf]], [[1gzm|1gzm]], [[1hzx|1hzx]], [[1jfp|1jfp]], [[1l9h|1l9h]], [[1ln6|1ln6]], [[1n3m|1n3m]], [[1nzs|1nzs]], [[1ov0|1ov0]], [[1ov1|1ov1]], [[1u19|1u19]], [[1vqx|1vqx]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4y OCA], [https://pdbe.org/2j4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j4y RCSB], [https://www.ebi.ac.uk/pdbsum/2j4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j4y ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 32: | Line 32: | ||
==See Also== | ==See Also== | ||
| - | *[[Rhodopsin|Rhodopsin]] | + | *[[Rhodopsin 3D structures|Rhodopsin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 20:43, 20 October 2021
Crystal structure of a rhodopsin stabilizing mutant expressed in mammalian cells
| |||||||||||
Categories: Bovin | Large Structures | Burghammer, M | Edwards, P C | Oprian, D D | Schertler, G F.X | Standfuss, J | Xie, G | Chromophore | G-protein coupled receptor | Glycoprotein | Integral membrane protein | Lipoprotein | Membrane | Palmitate | Phosphorylation | Photoreceptor | Photoreceptor protein | Receptor | Retinal protein | Sensory transduction | Signaling protein | Transducer | Transmembrane | Vision | Visual pigment

