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2vkp

From Proteopedia

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(New page: 200px<br /><applet load="2vkp" size="350" color="white" frame="true" align="right" spinBox="true" caption="2vkp, resolution 1.90&Aring;" /> '''CRYSTAL STRUCTURE OF...)
Current revision (21:00, 20 October 2021) (edit) (undo)
 
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[[Image:2vkp.jpg|left|200px]]<br /><applet load="2vkp" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2vkp, resolution 1.90&Aring;" />
 
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'''CRYSTAL STRUCTURE OF BTB DOMAIN FROM BTBD6'''<br />
 
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==About this Structure==
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==Crystal structure of BTB domain from BTBD6==
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2VKP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Mse+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Mse+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Mse+Binding+Site+For+Chain+A'>AC3</scene>, <scene name='pdbsite=AC4:Mse+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:Mse+Binding+Site+For+Chain+B'>AC5</scene>, <scene name='pdbsite=AC6:Mse+Binding+Site+For+Chain+B'>AC6</scene>, <scene name='pdbsite=AC7:Mse+Binding+Site+For+Chain+B'>AC7</scene>, <scene name='pdbsite=AC8:Mse+Binding+Site+For+Chain+B'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Chain+B'>AC9</scene> and <scene name='pdbsite=BC1:Edo+Binding+Site+For+Chain+B'>BC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKP OCA].
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<StructureSection load='2vkp' size='340' side='right'caption='[[2vkp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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[[Category: Homo sapiens]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2vkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKP FirstGlance]. <br>
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[[Category: Arrowsmith, C.H.]]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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[[Category: Bunkoczi, G.]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Cooper, C.D.O.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkp OCA], [https://pdbe.org/2vkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkp RCSB], [https://www.ebi.ac.uk/pdbsum/2vkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkp ProSAT]</span></td></tr>
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[[Category: Delft, F.Von.]]
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</table>
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[[Category: Edwards, A.]]
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== Function ==
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[[Category: Elkins, J.M.]]
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[[https://www.uniprot.org/uniprot/BTBD6_HUMAN BTBD6_HUMAN]] Adapter protein for the CUL3 E3 ubiquitin-protein ligase complex. Involved in late neuronal development and muscle formation (By similarity).
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[[Category: Filippakopoulos, P.]]
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== Evolutionary Conservation ==
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[[Category: Gileadi, O.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Knapp, S.]]
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Check<jmol>
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[[Category: Pike, A.C.W.]]
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<jmolCheckbox>
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[[Category: Salah, E.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkp_consurf.spt"</scriptWhenChecked>
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[[Category: Weigelt, J.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: EDO]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: K]]
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</jmolCheckbox>
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[[Category: protein-binding]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vkp ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 13 08:21:58 2008''
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__TOC__
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</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bunkoczi, G]]
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[[Category: Cooper, C D.O]]
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[[Category: Delft, F von]]
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[[Category: Edwards, A]]
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[[Category: Elkins, J M]]
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[[Category: Filippakopoulos, P]]
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[[Category: Gileadi, O]]
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[[Category: Knapp, S]]
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[[Category: Pike, A C.W]]
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[[Category: Salah, E]]
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[[Category: Weigelt, J]]
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[[Category: Protein binding]]
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[[Category: Protein-binding]]

Current revision

Crystal structure of BTB domain from BTBD6

PDB ID 2vkp

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