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1hwl
From Proteopedia
(Difference between revisions)
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<StructureSection load='1hwl' size='340' side='right'caption='[[1hwl]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1hwl' size='340' side='right'caption='[[1hwl]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1hwl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HWL FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1hwl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HWL FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=FBI:7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL]+-3,5-DIHYDROXY-HEPTANOIC+ACID'>FBI</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=FBI:7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL]+-3,5-DIHYDROXY-HEPTANOIC+ACID'>FBI</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dq8|1dq8]], [[1dq9|1dq9]], [[1dqa|1dqa]], [[1hw8|1hw8]], [[1hw9|1hw9]], [[1hwi|1hwi]], [[1hwj|1hwj]], [[1hwk|1hwk]]</div></td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dq8|1dq8]], [[1dq9|1dq9]], [[1dqa|1dqa]], [[1hw8|1hw8]], [[1hw9|1hw9]], [[1hwi|1hwi]], [[1hwj|1hwj]], [[1hwk|1hwk]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGCR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hwl OCA], [https://pdbe.org/1hwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hwl RCSB], [https://www.ebi.ac.uk/pdbsum/1hwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hwl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hwl OCA], [https://pdbe.org/1hwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hwl RCSB], [https://www.ebi.ac.uk/pdbsum/1hwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hwl ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Deisenhofer, J]] | [[Category: Deisenhofer, J]] | ||
Revision as of 14:20, 27 October 2021
COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ROSUVASTATIN (FORMALLY KNOWN AS ZD4522)
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