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MDM2 3D structures

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**[[6sqp]] - cMDM2 C4 ring-finger domain – cat<br />
**[[6sqp]] - cMDM2 C4 ring-finger domain – cat<br />
**[[4ipf]], [[4j74]] – fMDM2 p53-binding domain (mutant) - frog<br />
**[[4ipf]], [[4j74]] – fMDM2 p53-binding domain (mutant) - frog<br />
 +
**[[7ahy]] - fMDM2 RING domain <br />
 +
**[[7ah2]] - MDM2 RING domain – zebrafish<br />
*MDM2 p53-binding domain complex with small molecule
*MDM2 p53-binding domain complex with small molecule
**[[1rv1]], [[1t4e]], [[3lbk]], [[4dij]], [[3vzv]], [[3w69]], [[3lkb]], [[4lwt]], [[4lwu]], [[4lwv]], [[4oq3]], [[5hmh]], [[5hmi]], [[5hmk]] – hMDM2 (mutant) + inhibitor<br />
**[[1rv1]], [[1t4e]], [[3lbk]], [[4dij]], [[3vzv]], [[3w69]], [[3lkb]], [[4lwt]], [[4lwu]], [[4lwv]], [[4oq3]], [[5hmh]], [[5hmi]], [[5hmk]] – hMDM2 (mutant) + inhibitor<br />
-
**[[3jzk]], [[3lbl]], [[3tu1]], [[4ere]], [[4erf]], [[3tj2]], [[4hbm]], [[4jv7]], [[4jv9]], [[4jve]], [[4jvr]], [[4jwr]], [[4mdn]], [[4mdq]], [[4oas]], [[4oba]], [[4occ]], [[4ode]], [[4odf]], [[4ogn]], [[4ogt]], [[4ogv]], [[4qo4]], [[4hg7]], [[4wt2]], [[4qoc]], [[4wt2]], [[4zfi]], [[4zgk]], [[4zyf]], [[4zyi]], [[5j7f]], [[5j7g]], [[5lav]], [[5law]], [[5lay]], [[5laz]], [[5ln2]], [[5trf]], [[6q96]], [[6q9h]], [[6q9l]], [[6q9o]], [[6i3s]], [[6ggn]], [[5oc8]], [[5oai]], [[6i29]] - hMDM2 + inhibitor<br />
+
**[[3jzk]], [[3lbl]], [[3tu1]], [[4ere]], [[4erf]], [[3tj2]], [[4hbm]], [[4jv7]], [[4jv9]], [[4jve]], [[4jvr]], [[4jwr]], [[4mdn]], [[4mdq]], [[4oas]], [[4oba]], [[4occ]], [[4ode]], [[4odf]], [[4ogn]], [[4ogt]], [[4ogv]], [[4qo4]], [[4hg7]], [[4wt2]], [[4qoc]], [[4wt2]], [[4zfi]], [[4zgk]], [[4zyf]], [[4zyi]], [[5j7f]], [[5j7g]], [[5lav]], [[5law]], [[5lay]], [[5laz]], [[5ln2]], [[5trf]], [[6q96]], [[6q9h]], [[6q9l]], [[6q9o]], [[6i3s]], [[6ggn]], [[5oc8]], [[5oai]], [[6i29]], [[7bir]], [[7bit]], [[7biv]], [[7bj0]], [[7bj6]], [[7bmg]] - hMDM2 + inhibitor<br />
**[[5z02]], [[5zxf]] - hMDM2 +  nutlin<br />
**[[5z02]], [[5zxf]] - hMDM2 +  nutlin<br />
**[[2lzg]] - hMDM2 + inhibitor – NMR<br />
**[[2lzg]] - hMDM2 + inhibitor – NMR<br />
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**[[1t4f]], [[4hfz]] - hMDM2 (mutant) p53-binding domain + p53 peptide<br />
**[[1t4f]], [[4hfz]] - hMDM2 (mutant) p53-binding domain + p53 peptide<br />
-
**[[3v3b]] - hMDM2 p53-binding domain + p53 peptide<br />
+
**[[3v3b]], [[7ad0]], [[7nus]] - hMDM2 p53-binding domain + p53 peptide<br />
**[[2mps]] - hMDM2 p53-binding domain + p73 peptide<br />
**[[2mps]] - hMDM2 p53-binding domain + p73 peptide<br />
**[[3jzr]] - hMDM2 p53-binding domain + pDI6W peptide<br />
**[[3jzr]] - hMDM2 p53-binding domain + pDI6W peptide<br />
Line 46: Line 48:
**[[5swk]] - hMDM2  p53-binding domain + cysteine protease inhibitor<br />
**[[5swk]] - hMDM2  p53-binding domain + cysteine protease inhibitor<br />
**[[6im9]] - hMDM2  p53-binding domain + copper reflux oxidase<br />
**[[6im9]] - hMDM2  p53-binding domain + copper reflux oxidase<br />
 +
**[[7aye]] - hMDM2  p53-binding domain + DsbD<br />
**[[6sqo]] - hMDM2  ring domain + ubiquitin-conjugating enzyme E2 + S27A<br />
**[[6sqo]] - hMDM2  ring domain + ubiquitin-conjugating enzyme E2 + S27A<br />
**[[6sqr]], [[6sqs]] - cMDM2  ring domain + ubiquitin-conjugating enzyme E2 + S27A<br />
**[[6sqr]], [[6sqs]] - cMDM2  ring domain + ubiquitin-conjugating enzyme E2 + S27A<br />
 +
**[[7ahz]], [[7ai0]], [[7ai1]] - fMDM2 RING domain (mutant) + polyubiquitin + ubiquitin-conjugating enzyme E2<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:17, 28 October 2021

3D structures of MDM2

Updated on 28-October-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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