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Metabotropic glutamate receptor 3D structures

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(New page: ==3D structures of metabotropic glutamate receptor == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Metabotropic...)
Line 6: Line 6:
*Metabotropic glutamate receptor 1
*Metabotropic glutamate receptor 1
-
**[[3ks9]] – hMGluR1 (mutant) + antagonist - human<br />
+
**[[7gdg]] – hMGluR1 - human – Cryo EM<br />
 +
**[[7dge]] – hMGluR1 + nanobody – Cryo EM<br />
 +
**[[3ks9]] – hMGluR1 (mutant) + antagonist<br />
**[[4or2]] - hMGluR1/cytochrome b526<br />
**[[4or2]] - hMGluR1/cytochrome b526<br />
**[[1ewt]], [[1ewv]] - rMGluR1 LBD - rat<br />
**[[1ewt]], [[1ewv]] - rMGluR1 LBD - rat<br />
Line 12: Line 14:
**[[1iss]] - rMGluR1 LBD + antagonist<br />
**[[1iss]] - rMGluR1 LBD + antagonist<br />
-
*Metabotropic glutamate receptor 2
+
*Metabotropic glutamate receptor 2; Domains – LBD 1-564
 +
**[[7epa]] – hMGluR2 – Cryo EM<br />
 +
**[[7epd]] – hMGluR2/GluR7 – Cryo EM<br />
 +
**[[7epb]] – hMGluR2 (mutant) + nanobody – Cryo EM<br />
 +
**[[7mtq]] – hMGluR2 + antagonist – Cryo EM<br />
 +
**[[7mtr]] – hMGluR2 + antagonist + Glu – Cryo EM<br />
 +
**[[7mts]] – hMGluR2 in Gi complex + Glu – Cryo EM<br />
 +
**[[7e9g]] – hMGluR2 (mutant) in Gi complex + antagonist + scFv – Cryo EM<br />
**[[4xas]], [[4xaq]] – hMGluR2 LBD + agonist<br />
**[[4xas]], [[4xaq]] – hMGluR2 LBD + agonist<br />
**[[5kzq]], [[5kzn]] – hMGluR2 LBD + antagonist<br />
**[[5kzq]], [[5kzn]] – hMGluR2 LBD + antagonist<br />
**[[5cni]] – hMGluR2 LBD + Glu <br />
**[[5cni]] – hMGluR2 LBD + Glu <br />
**[[5cnj]] – hMGluR2 LBD + Glu analog<br />
**[[5cnj]] – hMGluR2 LBD + Glu analog<br />
 +
**[[7epe}}, [[7epf]] – hMGluR2 547-853 + antagonist + FMN<br />
*Metabotropic glutamate receptor 3
*Metabotropic glutamate receptor 3
Line 27: Line 37:
**[[2e4u]] – rMGluR3 LBD (mutant) + Glu<br />
**[[2e4u]] – rMGluR3 LBD (mutant) + Glu<br />
**[[2e4v]], [[2e4w]], [[2e4x]], [[2e4y]], [[2e4z]] - rMGluR3 LBD (mutant) + agonist<br />
**[[2e4v]], [[2e4w]], [[2e4x]], [[2e4y]], [[2e4z]] - rMGluR3 LBD (mutant) + agonist<br />
 +
 +
*Metabotropic glutamate receptor 4
 +
 +
**[[7e9h]] – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM<br />
*Metabotropic glutamate receptor 5
*Metabotropic glutamate receptor 5
**[[6n52]] – hMGluR5 – Cryo EM<br />
**[[6n52]] – hMGluR5 – Cryo EM<br />
 +
**[[7fd8]], [[7fd9]] – hMGluR5 + antagonist – Cryo EM<br />
**[[6n51]], [[6n50]], [[6n4y]] – hMGluR5 + nanobody – Cryo EM<br />
**[[6n51]], [[6n50]], [[6n4y]] – hMGluR5 + nanobody – Cryo EM<br />
**[[6n4x]] – hMGluR5 LBD<br />
**[[6n4x]] – hMGluR5 LBD<br />
Line 36: Line 51:
**[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu<br />
**[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu<br />
**[[5cgc]], [[5cgd]] - hMGluR5 transmembrane domain + negative allosteric modulator<br />
**[[5cgc]], [[5cgd]] - hMGluR5 transmembrane domain + negative allosteric modulator<br />
 +
**[[7p2l]] - hMGluR5 transmembrane domain (mutant) 569-836 + negative allosteric modulator<br />
*Metabotropic glutamate receptor 7
*Metabotropic glutamate receptor 7
 +
**[[7epc]] – hMGluR7 – Cryo EM<br />
**[[5c5c]] – hMGluR7 LBD (mutant)<br />
**[[5c5c]] – hMGluR7 LBD (mutant)<br />
**[[3mq4]] – hMGluR7 LBD + antagonist<br />
**[[3mq4]] – hMGluR7 LBD + antagonist<br />

Revision as of 10:59, 31 October 2021

3D structures of metabotropic glutamate receptor

Updated on 31-October-2021 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Metabotropic glutamate receptor 1
    • 7gdg – hMGluR1 - human – Cryo EM
    • 7dge – hMGluR1 + nanobody – Cryo EM
    • 3ks9 – hMGluR1 (mutant) + antagonist
    • 4or2 - hMGluR1/cytochrome b526
    • 1ewt, 1ewv - rMGluR1 LBD - rat
    • 1isr, 1ewk – rMGluR1 LBD + Glu
    • 1iss - rMGluR1 LBD + antagonist
  • Metabotropic glutamate receptor 2; Domains – LBD 1-564
    • 7epa – hMGluR2 – Cryo EM
    • 7epd – hMGluR2/GluR7 – Cryo EM
    • 7epb – hMGluR2 (mutant) + nanobody – Cryo EM
    • 7mtq – hMGluR2 + antagonist – Cryo EM
    • 7mtr – hMGluR2 + antagonist + Glu – Cryo EM
    • 7mts – hMGluR2 in Gi complex + Glu – Cryo EM
    • 7e9g – hMGluR2 (mutant) in Gi complex + antagonist + scFv – Cryo EM
    • 4xas, 4xaq – hMGluR2 LBD + agonist
    • 5kzq, 5kzn – hMGluR2 LBD + antagonist
    • 5cni – hMGluR2 LBD + Glu
    • 5cnj – hMGluR2 LBD + Glu analog
    • [[7epe}}, 7epf – hMGluR2 547-853 + antagonist + FMN
  • Metabotropic glutamate receptor 3
    • 5cnk – hMGluR3 LBD + Glu
    • 3sm9 - hMGluR3 + antagonist
    • 4xar, 6b7h – hMGluR3 LBD + agonist
    • 5cnm – hMGluR3 LBD + Glu analog
    • 2e4u – rMGluR3 LBD (mutant) + Glu
    • 2e4v, 2e4w, 2e4x, 2e4y, 2e4z - rMGluR3 LBD (mutant) + agonist
  • Metabotropic glutamate receptor 4
    • 7e9h – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM
  • Metabotropic glutamate receptor 5
    • 6n52 – hMGluR5 – Cryo EM
    • 7fd8, 7fd9 – hMGluR5 + antagonist – Cryo EM
    • 6n51, 6n50, 6n4y – hMGluR5 + nanobody – Cryo EM
    • 6n4x – hMGluR5 LBD
    • 6ffh, 6ffi - hMGluR5 LBD (mutant) + positive allosteric modulator
    • 3lmk – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu
    • 5cgc, 5cgd - hMGluR5 transmembrane domain + negative allosteric modulator
    • 7p2l - hMGluR5 transmembrane domain (mutant) 569-836 + negative allosteric modulator
  • Metabotropic glutamate receptor 7
    • 7epc – hMGluR7 – Cryo EM
    • 5c5c – hMGluR7 LBD (mutant)
    • 3mq4 – hMGluR7 LBD + antagonist
  • Metabotropic glutamate receptor 8
    • 6bsz – hMGluR8 LBD + Glu
    • 6bt5 – hMGluR8 LBD + phosphonobutanoic acid
    • 6e5v – hMGluR8 N-terminal (mutant) + inhibitor

}}

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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