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7f1x

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==X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate==
==X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate==
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<StructureSection load='7f1x' size='340' side='right'caption='[[7f1x]]' scene=''>
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<StructureSection load='7f1x' size='340' side='right'caption='[[7f1x]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F1X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7f1x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F1X FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f1x OCA], [https://pdbe.org/7f1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f1x RCSB], [https://www.ebi.ac.uk/pdbsum/7f1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f1x ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene>, <scene name='pdbligand=PTD:PENTANEDIAL'>PTD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f1x OCA], [https://pdbe.org/7f1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f1x RCSB], [https://www.ebi.ac.uk/pdbsum/7f1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f1x ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Note=S-antigen induces autoimmune uveitis.
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== Function ==
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[[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Choe HW]]
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[[Category: Choe, H W]]
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[[Category: Eger BT]]
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[[Category: Eger, B T]]
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[[Category: Ernst OP]]
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[[Category: Ernst, O P]]
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[[Category: Jang K]]
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[[Category: Jang, K]]
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[[Category: Kang M]]
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[[Category: Kang, M]]
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[[Category: Kim YJ]]
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[[Category: Kim, Y J]]
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[[Category: Signaling protein]]

Revision as of 15:58, 3 November 2021

X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate

PDB ID 7f1x

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