This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2wnt
From Proteopedia
(New page: '''Unreleased structure''' The entry 2wnt is ON HOLD Authors: Muniz, J.R.C., Elkins, J.M., Wang, J., Ugochukwu, E., Salah, E., King, O., Picaud, S., Von Delft, F., Bountra, C., Arrowsmi...) |
|||
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Human Ribosomal protein S6 kinase== | |
| + | <StructureSection load='2wnt' size='340' side='right'caption='[[2wnt]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2wnt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNT FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnt OCA], [https://pdbe.org/2wnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnt RCSB], [https://www.ebi.ac.uk/pdbsum/2wnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnt_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wnt ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Ribosomal protein S6 kinase|Ribosomal protein S6 kinase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Elkins, J M]] | ||
| + | [[Category: King, O]] | ||
| + | [[Category: Knapp, S]] | ||
| + | [[Category: Muniz, J R.C]] | ||
| + | [[Category: Picaud, S]] | ||
| + | [[Category: Salah, E]] | ||
| + | [[Category: Ugochukwu, E]] | ||
| + | [[Category: Wang, J]] | ||
| + | [[Category: Weigelt, J]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Ribosomal]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Transferase]] | ||
Current revision
Crystal Structure of the Human Ribosomal protein S6 kinase
| |||||||||||
Categories: Large Structures | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Delft, F von | Edwards, A | Elkins, J M | King, O | Knapp, S | Muniz, J R.C | Picaud, S | Salah, E | Ugochukwu, E | Wang, J | Weigelt, J | Atp-binding | Human | Kinase | Magnesium | Metal-binding | Nucleotide-binding | Phosphoprotein | Polymorphism | Ribosomal | Serine/threonine-protein kinase | Transferase

