This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ie1
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA== | ==Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA== | ||
| - | <StructureSection load='3ie1' size='340' side='right' caption='[[3ie1]], [[Resolution|resolution]] 2.85Å' scene=''> | + | <StructureSection load='3ie1' size='340' side='right'caption='[[3ie1]], [[Resolution|resolution]] 2.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ie1]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ie1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zde 2zde]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IE1 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dkf|2dkf]], [[3a4y|3a4y]], [[3idz|3idz]], [[3ie0|3ie0]], [[3ie2|3ie2]], [[3iek|3iek]], [[3iel|3iel]], [[3iem|3iem]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dkf|2dkf]], [[3a4y|3a4y]], [[3idz|3idz]], [[3ie0|3ie0]], [[3ie2|3ie2]], [[3iek|3iek]], [[3iel|3iel]], [[3iem|3iem]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0252 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0252 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ie1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ie1 OCA], [https://pdbe.org/3ie1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ie1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ie1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ie1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RNSE_THET8 RNSE_THET8]] Has endoribonuclease activity towards 23S and 16S rRNA (in vitro). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ie1_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ie1_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 23: | Line 23: | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thet8]] | [[Category: Thet8]] | ||
[[Category: Ishikawa, H]] | [[Category: Ishikawa, H]] | ||
Revision as of 07:47, 10 November 2021
Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA
| |||||||||||
Categories: Large Structures | Thet8 | Ishikawa, H | Kuramitsu, S | Masui, R | Nakagawa, N | Structural genomic | Yokoyama, S | Endonuclease | Hydrolase-rna complex | Metal-binding | Metallo beta lactamase fold | National project on protein structural and functional analyse | Nppsfa | Nuclease | Rna-binding | Rrna processing | Rsgi
