Androgen receptor

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D: Hinge region between DBD and LBD<br />
D: Hinge region between DBD and LBD<br />
E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/3'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif.<ref>PMID:18805694</ref> Water molecules are shown as red spheres. <br />
E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/3'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif.<ref>PMID:18805694</ref> Water molecules are shown as red spheres. <br />
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F: C-terminal domain
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F: C-terminal domain.
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<scene name='89/895670/Cv/6'>Human androgen receptor bound to testosterone</scene> ([[2ylo]]).
== 3D Structures of androgen receptor ==
== 3D Structures of androgen receptor ==

Revision as of 12:36, 14 November 2021

Human androgen receptor ligand-binding domain complex with modulator (PDB code 3b5r)

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See Also

References

  1. Bohl CE, Wu Z, Chen J, Mohler ML, Yang J, Hwang DJ, Mustafa S, Miller DD, Bell CE, Dalton JT. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5567-70. Epub 2008 Sep 5. PMID:18805694 doi:10.1016/j.bmcl.2008.09.002
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