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2xvt
From Proteopedia
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<StructureSection load='2xvt' size='340' side='right'caption='[[2xvt]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='2xvt' size='340' side='right'caption='[[2xvt]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xvt]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xvt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XVT FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvt OCA], [https://pdbe.org/2xvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xvt RCSB], [https://www.ebi.ac.uk/pdbsum/2xvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xvt ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RAMP2_HUMAN RAMP2_HUMAN]] Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.<ref>PMID:22102369</ref> <ref>PMID:9620797</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 14:55, 17 November 2021
Structure of the extracellular domain of human RAMP2
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Categories: Human | Large Structures | Arrowsmith, C H | Barr, A J | Bountra, C | Burgess-Brown, N | Canning, P | Carpenter, E P | Chaikuad, A | Das, S | Delft, F von | Edwards, A M | Goubin, S | Kim, J | Krojer, T | Muniz, J R.C | Pike, A C.W | Quigley, A | Shrestha, L | Vollmar, M | Weigelt, J | Adrenomedulin | Cgrp | Crlr | Gpcr | Membrane protein | Protein-trafficking | Receptor transport | Transmembrane
