This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2dhh
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2dhh' size='340' side='right'caption='[[2dhh]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='2dhh' size='340' side='right'caption='[[2dhh]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dhh]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dhh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DHH FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dr6|2dr6]], [[2drd|2drd]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dr6|2dr6]], [[2drd|2drd]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dhh OCA], [https://pdbe.org/2dhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dhh RCSB], [https://www.ebi.ac.uk/pdbsum/2dhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dhh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:31, 8 December 2021
Crystal structure of a multidrug transporter reveal a functionally rotating mechanism
| |||||||||||

