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2dsy
From Proteopedia
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| - | [[Image:2dsy.gif|left|200px]] | ||
| - | + | ==Crystal structure of TTHA0281 from thermus thermophilus HB8== | |
| - | + | <StructureSection load='2dsy' size='340' side='right'caption='[[2dsy]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2dsy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DSY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | | | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dsy OCA], [https://pdbe.org/2dsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dsy RCSB], [https://www.ebi.ac.uk/pdbsum/2dsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dsy ProSAT], [https://www.topsan.org/Proteins/RSGI/2dsy TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/2dsy_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | == | + | <text>to colour the structure by Evolutionary Conservation</text> |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dsy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
TTHA0281 is a hypothetical protein from Thermus thermophilus HB8 that belongs to an uncharacterized protein family, UPF0150, in the Pfam database and to COG1598 in the National Center for Biotechnology Information Database of Clusters of Orthologous Groups. The X-ray crystal structure of the protein was determined by a multiple-wavelength anomalous dispersion technique and was refined at 1.9 A resolution to a final R factor of 18.5%. The TTHA0281 monomer adopts an alpha-beta-beta-beta-alpha fold and forms a homotetramer. Based on the properties and functions of structural homologues of the TTHA0281 monomer, the TTHA0281 protein is speculated to be involved in RNA metabolism, including RNA binding and cleavage. | TTHA0281 is a hypothetical protein from Thermus thermophilus HB8 that belongs to an uncharacterized protein family, UPF0150, in the Pfam database and to COG1598 in the National Center for Biotechnology Information Database of Clusters of Orthologous Groups. The X-ray crystal structure of the protein was determined by a multiple-wavelength anomalous dispersion technique and was refined at 1.9 A resolution to a final R factor of 18.5%. The TTHA0281 monomer adopts an alpha-beta-beta-beta-alpha fold and forms a homotetramer. Based on the properties and functions of structural homologues of the TTHA0281 monomer, the TTHA0281 protein is speculated to be involved in RNA metabolism, including RNA binding and cleavage. | ||
| - | + | Structure of a UPF0150-family protein from Thermus thermophilus HB8.,Okazaki N, Kumei M, Manzoku M, Kuramitsu S, Shirouzu M, Shinkai A, Yokoyama S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):173-7. Epub 2007 Feb 23. PMID:17329807<ref>PMID:17329807</ref> | |
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| - | Structure of a UPF0150-family protein from Thermus thermophilus HB8., Okazaki N, Kumei M, Manzoku M, Kuramitsu S, Shirouzu M, Shinkai A, Yokoyama S | + | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 2dsy" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Flavobacterium thermophilum yoshida and oshima 1971]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kumei, M]] | ||
| + | [[Category: Okazaki, N]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Shinkai, A]] | ||
| + | [[Category: Yokoyama, S]] | ||
| + | [[Category: Hypothetical protein]] | ||
| + | [[Category: National project on protein structural and functional analyse]] | ||
| + | [[Category: Nppsfa]] | ||
| + | [[Category: Rsgi]] | ||
| + | [[Category: Thermus thermophilus hb8]] | ||
| + | [[Category: Unknown function]] | ||
Current revision
Crystal structure of TTHA0281 from thermus thermophilus HB8
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Categories: Flavobacterium thermophilum yoshida and oshima 1971 | Large Structures | Kumei, M | Okazaki, N | Structural genomic | Shinkai, A | Yokoyama, S | Hypothetical protein | National project on protein structural and functional analyse | Nppsfa | Rsgi | Thermus thermophilus hb8 | Unknown function
