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2z04
From Proteopedia
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| - | [[Image:2z04.png|left|200px]] | ||
| - | + | ==Crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit from Aquifex aeolicus== | |
| + | <StructureSection load='2z04' size='340' side='right'caption='[[2z04]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2z04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z04 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z04 OCA], [https://pdbe.org/2z04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z04 RCSB], [https://www.ebi.ac.uk/pdbsum/2z04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z04 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z04 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PURK_AQUAE PURK_AQUAE]] Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z04_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z04 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Phosphoribosylaminoimidazole carboxylase 3D structures|Phosphoribosylaminoimidazole carboxylase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Aquifex aeolicus huber and stetter 2001]] |
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Phosphoribosylaminoimidazole carboxylase]] | [[Category: Phosphoribosylaminoimidazole carboxylase]] | ||
| - | [[Category: Baba, S | + | [[Category: Baba, S]] |
| - | [[Category: Kanagawa, M | + | [[Category: Kanagawa, M]] |
| - | [[Category: Kawai, G | + | [[Category: Kawai, G]] |
| - | [[Category: Okada, K | + | [[Category: Okada, K]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sampei, G | + | [[Category: Sampei, G]] |
| - | [[Category: Tamura, S | + | [[Category: Tamura, S]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Decarboxylase]] | [[Category: Decarboxylase]] | ||
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[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
[[Category: Purine nucleotide biosynthetic pathway]] | [[Category: Purine nucleotide biosynthetic pathway]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Current revision
Crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit from Aquifex aeolicus
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Categories: Aquifex aeolicus huber and stetter 2001 | Large Structures | Phosphoribosylaminoimidazole carboxylase | Baba, S | Kanagawa, M | Kawai, G | Okada, K | Structural genomic | Sampei, G | Tamura, S | Atp-binding | Decarboxylase | Lyase | Metabolic system | National project on protein structural and functional analyse | Nppsfa | Nucleotide-binding | Purine biosynthesis | Purine nucleotide biosynthetic pathway | Rsgi
