This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2zop
From Proteopedia
(Difference between revisions)
m (Protected "2zop" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2zop.png|left|200px]] | ||
| - | + | ==X-ray crystal structure of a CRISPR-associated Cmr5 family protein from Thermus thermophilus HB8== | |
| - | + | <StructureSection load='2zop' size='340' side='right'caption='[[2zop]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2zop]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[2zop]] is a 6 chain structure with sequence from [ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHB164 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zop OCA], [https://pdbe.org/2zop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zop RCSB], [https://www.ebi.ac.uk/pdbsum/2zop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zop ProSAT], [https://www.topsan.org/Proteins/RSGI/2zop TOPSAN]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| - | [[Category: | + | [[https://www.uniprot.org/uniprot/CMR5_THET8 CMR5_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Part of the Cmr ribonucleoprotein complex (By similarity). |
| - | [[Category: Agari, Y | + | == Evolutionary Conservation == |
| - | [[Category: Kuramitsu, S | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: | + | Check<jmol> |
| - | [[Category: Sakamoto, K | + | <jmolCheckbox> |
| - | [[Category: Shinkai, A | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zop_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Yokoyama, S | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zop ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thet8]] | ||
| + | [[Category: Agari, Y]] | ||
| + | [[Category: Kuramitsu, S]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Sakamoto, K]] | ||
| + | [[Category: Shinkai, A]] | ||
| + | [[Category: Yokoyama, S]] | ||
[[Category: All alpha protein]] | [[Category: All alpha protein]] | ||
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
| - | [[Category: | + | [[Category: Plasmid]] |
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Current revision
X-ray crystal structure of a CRISPR-associated Cmr5 family protein from Thermus thermophilus HB8
| |||||||||||
