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2ew2
From Proteopedia
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| - | [[Image:2ew2.gif|left|200px]]<br /><applet load="2ew2" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2ew2, resolution 2.00Å" /> | ||
| - | '''Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis'''<br /> | ||
| - | == | + | ==Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis== |
| - | + | <StructureSection load='2ew2' size='340' side='right'caption='[[2ew2]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2ew2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Entfa Entfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EW2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [https://pdbe.org/2ew2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ew2 ProSAT], [https://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/Q831Q5_ENTFA Q831Q5_ENTFA]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).[RuleBase:RU003776] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ew2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ew2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: 2-dehydropantoate 2-reductase]] | [[Category: 2-dehydropantoate 2-reductase]] | ||
| - | [[Category: | + | [[Category: Entfa]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Clancy, S | + | [[Category: Clancy, S]] |
| - | [[Category: Collart, F | + | [[Category: Collart, F]] |
| - | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Kim, Y | + | [[Category: Kim, Y]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Moy, S | + | [[Category: Moy, S]] |
| - | [[Category: Zhou, M | + | [[Category: Zhou, M]] |
| - | [[Category: | + | [[Category: Alpha-beta structure]] |
| - | + | [[Category: Alpha-structure]] | |
| - | + | [[Category: Mcsg]] | |
| - | [[Category: | + | [[Category: Oxidoreductase]] |
| - | [[Category: | + | [[Category: PSI, Protein structure initiative]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
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Current revision
Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis
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