This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2jcn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:07, 22 December 2021) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2jcn.gif|left|200px]]<br /><applet load="2jcn" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2jcn, resolution 1.80&Aring;" />
 
-
'''THE CRYSTAL STRUCTURE OF BAK1- A MITOCHONDRIAL APOPTOSIS REGULATOR'''<br />
 
-
==About this Structure==
+
==The crystal structure of BAK1 - a mitochondrial apoptosis regulator==
-
2JCN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:So4 Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCN OCA].
+
<StructureSection load='2jcn' size='340' side='right'caption='[[2jcn]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2jcn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCN FirstGlance]. <br>
-
[[Category: Arrowsmith, C.]]
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Berg, S.Van.Den.]]
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bxl|1bxl]]</div></td></tr>
-
[[Category: Berglund, H.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcn OCA], [https://pdbe.org/2jcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcn RCSB], [https://www.ebi.ac.uk/pdbsum/2jcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcn ProSAT]</span></td></tr>
-
[[Category: Busam, R.]]
+
</table>
-
[[Category: Collins, R.]]
+
== Evolutionary Conservation ==
-
[[Category: Edwards, A.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Ericsson, U.B.]]
+
Check<jmol>
-
[[Category: Flodin, S.]]
+
<jmolCheckbox>
-
[[Category: Flores, A.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcn_consurf.spt"</scriptWhenChecked>
-
[[Category: Graslund, S.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Hallberg, B.M.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Hammarstrom, M.]]
+
</jmolCheckbox>
-
[[Category: Johansson, I.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jcn ConSurf].
-
[[Category: Karlberg, T.]]
+
<div style="clear:both"></div>
-
[[Category: Kosinska, U.]]
+
__TOC__
-
[[Category: Kotenyova, T.]]
+
</StructureSection>
-
[[Category: Lundgren, S.]]
+
[[Category: Human]]
-
[[Category: Moche, M.]]
+
[[Category: Large Structures]]
-
[[Category: Nilsson, M.E.]]
+
[[Category: Arrowsmith, C]]
-
[[Category: Nordlund, P.]]
+
[[Category: Berg, S van den]]
-
[[Category: Nyman, T.]]
+
[[Category: Berglund, H]]
-
[[Category: Ogg, D.]]
+
[[Category: Busam, R]]
-
[[Category: Persson, C.]]
+
[[Category: Collins, R]]
-
[[Category: Sagemark, J.]]
+
[[Category: Edwards, A]]
-
[[Category: Schiavone, L.Holmberg.]]
+
[[Category: Ericsson, U B]]
-
[[Category: Stenmark, P.]]
+
[[Category: Flodin, S]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Flores, A]]
-
[[Category: Thorsell, A.G.]]
+
[[Category: Graslund, S]]
-
[[Category: Uppenberg, J.]]
+
[[Category: Hallberg, B M]]
-
[[Category: Upsten, M.]]
+
[[Category: Hammarstrom, M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Johansson, I]]
-
[[Category: SO4]]
+
[[Category: Karlberg, T]]
-
[[Category: apoptosis]]
+
[[Category: Kosinska, U]]
-
[[Category: cytochrome c release]]
+
[[Category: Kotenyova, T]]
-
[[Category: membrane]]
+
[[Category: Lundgren, S]]
-
[[Category: mitochondrial outer membrane permeabilization]]
+
[[Category: Moche, M]]
-
[[Category: oligomerization]]
+
[[Category: Nilsson, M E]]
-
[[Category: polymorphism]]
+
[[Category: Nordlund, P]]
-
[[Category: transmembrane]]
+
[[Category: Nyman, T]]
-
 
+
[[Category: Ogg, D]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:18:42 2008''
+
[[Category: Persson, C]]
 +
[[Category: Structural genomic]]
 +
[[Category: Sagemark, J]]
 +
[[Category: Schiavone, L Holmberg]]
 +
[[Category: Stenmark, P]]
 +
[[Category: Sundstrom, M]]
 +
[[Category: Thorsell, A G]]
 +
[[Category: Uppenberg, J]]
 +
[[Category: Upsten, M]]
 +
[[Category: Weigelt, J]]
 +
[[Category: Apoptosis]]
 +
[[Category: Cytochrome c release]]
 +
[[Category: Membrane]]
 +
[[Category: Mitochondrial outer membrane permeabilization]]
 +
[[Category: Oligomerization]]
 +
[[Category: Transmembrane]]

Current revision

The crystal structure of BAK1 - a mitochondrial apoptosis regulator

PDB ID 2jcn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools