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3afn

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==Crystal structure of aldose reductase A1-R complexed with NADP==
==Crystal structure of aldose reductase A1-R complexed with NADP==
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<StructureSection load='3afn' size='340' side='right' caption='[[3afn]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
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<StructureSection load='3afn' size='340' side='right'caption='[[3afn]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3afn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphingomonas_sp._a1 Sphingomonas sp. a1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AFN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3afn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingomonas_sp._a1 Sphingomonas sp. a1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AFN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3afm|3afm]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3afm|3afm]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">a1-R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90322 Sphingomonas sp. A1])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">a1-R ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90322 Sphingomonas sp. A1])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydro-3-deoxy-D-gluconate_6-dehydrogenase 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.126 1.1.1.126] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-dehydro-3-deoxy-D-gluconate_6-dehydrogenase 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.126 1.1.1.126] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3afn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3afn OCA], [http://pdbe.org/3afn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3afn RCSB], [http://www.ebi.ac.uk/pdbsum/3afn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3afn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3afn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3afn OCA], [https://pdbe.org/3afn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3afn RCSB], [https://www.ebi.ac.uk/pdbsum/3afn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3afn ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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==See Also==
==See Also==
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*[[Aldose Reductase|Aldose Reductase]]
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*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
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*[[Carbonyl reductase|Carbonyl reductase]]
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*[[Carbonyl reductase 3D structures|Carbonyl reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase]]
[[Category: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase]]
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[[Category: Large Structures]]
[[Category: Sphingomonas sp. a1]]
[[Category: Sphingomonas sp. a1]]
[[Category: Hashimoto, W]]
[[Category: Hashimoto, W]]

Revision as of 16:26, 22 December 2021

Crystal structure of aldose reductase A1-R complexed with NADP

PDB ID 3afn

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