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2gtq

From Proteopedia

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[[Image:2gtq.gif|left|200px]]<br /><applet load="2gtq" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2gtq, resolution 2.05&Aring;" />
 
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'''Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis'''<br />
 
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==About this Structure==
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==Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis==
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2GTQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_mc58 Neisseria meningitidis mc58] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTQ OCA].
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<StructureSection load='2gtq' size='340' side='right'caption='[[2gtq]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2gtq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GTQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gtq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gtq OCA], [https://pdbe.org/2gtq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gtq RCSB], [https://www.ebi.ac.uk/pdbsum/2gtq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gtq ProSAT], [https://www.topsan.org/Proteins/MCSG/2gtq TOPSAN]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gt/2gtq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gtq ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis., Nocek B, Mulligan R, Bargassa M, Collart F, Joachimiak A, Proteins. 2008 Jan 1;70(1):273-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17876832 17876832]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Membrane alanyl aminopeptidase]]
[[Category: Membrane alanyl aminopeptidase]]
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[[Category: Neisseria meningitidis mc58]]
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[[Category: Neimb]]
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[[Category: Single protein]]
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[[Category: Bargassa, M]]
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[[Category: Bargassa, M.]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak, A.]]
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[[Category: Structural genomic]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Mulligan, R]]
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[[Category: Mulligan, R.]]
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[[Category: Nocek, B]]
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[[Category: Nocek, B.]]
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[[Category: Alanine aminopeptidase]]
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[[Category: SO4]]
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[[Category: Aminopeptidase n]]
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[[Category: ZN]]
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[[Category: Hydrolase]]
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[[Category: alanine aminopeptidase]]
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[[Category: M1 family peptidase]]
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[[Category: aminopeptidase n]]
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[[Category: Mcsg]]
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[[Category: hydrolase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: m1 family peptidases]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomics]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:35:16 2008''
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Current revision

Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis

PDB ID 2gtq

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