This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3c07

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:38, 27 January 2022) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3c07.jpg|left|200px]]<br /><applet load="3c07" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="3c07, resolution 2.70&Aring;" />
 
-
'''Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)'''<br />
 
-
==About this Structure==
+
==Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)==
-
3C07 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+252'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+253'>AC2</scene> and <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+B+252'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C07 OCA].
+
<StructureSection load='3c07' size='340' side='right'caption='[[3c07]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
[[Category: Bacteria]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[3c07]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strco Strco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ofl 2ofl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C07 FirstGlance]. <br>
-
[[Category: Edwards, A.M.]]
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Joachimiak, A.]]
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO4850, SC5G8.18c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
-
[[Category: Savchenko, A.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c07 OCA], [https://pdbe.org/3c07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c07 RCSB], [https://www.ebi.ac.uk/pdbsum/3c07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c07 ProSAT], [https://www.topsan.org/Proteins/MCSG/3c07 TOPSAN]</span></td></tr>
-
[[Category: Tan, K.]]
+
</table>
-
[[Category: Xu, X.]]
+
== Evolutionary Conservation ==
-
[[Category: Zheng, H.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: SO4]]
+
Check<jmol>
-
[[Category: apc6322]]
+
<jmolCheckbox>
-
[[Category: dna-binding]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/3c07_consurf.spt"</scriptWhenChecked>
-
[[Category: mcsg]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: midwest center for structural genomics]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: protein structure initiative]]
+
</jmolCheckbox>
-
[[Category: psi-2]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c07 ConSurf].
-
[[Category: streptomyces coelicolor a3(2)]]
+
<div style="clear:both"></div>
-
[[Category: structural genomics]]
+
__TOC__
-
[[Category: tetr]]
+
</StructureSection>
-
[[Category: transcription]]
+
[[Category: Large Structures]]
-
[[Category: transcription regulation]]
+
[[Category: Strco]]
-
[[Category: transcription regulator]]
+
[[Category: Edwards, A M]]
-
 
+
[[Category: Joachimiak, A]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 6 17:26:57 2008''
+
[[Category: Structural genomic]]
 +
[[Category: Savchenko, A]]
 +
[[Category: Tan, K]]
 +
[[Category: Xu, X]]
 +
[[Category: Zheng, H]]
 +
[[Category: Apc6322]]
 +
[[Category: Dna-binding]]
 +
[[Category: Mcsg]]
 +
[[Category: PSI, Protein structure initiative]]
 +
[[Category: Tetr]]
 +
[[Category: Transcription]]
 +
[[Category: Transcription regulation]]
 +
[[Category: Transcription regulator]]

Current revision

Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)

PDB ID 3c07

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools