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3dz2
From Proteopedia
(Difference between revisions)
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==Human AdoMetDC with 5'-[(3-aminopropyl)methylamino]-5'deoxy-8-methyladenosine== | ==Human AdoMetDC with 5'-[(3-aminopropyl)methylamino]-5'deoxy-8-methyladenosine== | ||
| - | <StructureSection load='3dz2' size='340' side='right' caption='[[3dz2]], [[Resolution|resolution]] 1.86Å' scene=''> | + | <StructureSection load='3dz2' size='340' side='right'caption='[[3dz2]], [[Resolution|resolution]] 1.86Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3dz2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3dz2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DZ2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A8M:5-[(3-AMINOPROPYL)(METHYL)AMINO]-5-DEOXY-8-METHYLADENOSINE'>A8M</scene>, <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A8M:5-[(3-AMINOPROPYL)(METHYL)AMINO]-5-DEOXY-8-METHYLADENOSINE'>A8M</scene>, <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jen|1jen]], [[1i72|1i72]], [[1i7b|1i7b]], [[1i7c|1i7c]], [[1i79|1i79]], [[1i7m|1i7m]], [[3dz3|3dz3]], [[3dz4|3dz4]], [[3dz5|3dz5]], [[3dz6|3dz6]], [[3dz7|3dz7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jen|1jen]], [[1i72|1i72]], [[1i7b|1i7b]], [[1i7c|1i7c]], [[1i79|1i79]], [[1i7m|1i7m]], [[3dz3|3dz3]], [[3dz4|3dz4]], [[3dz5|3dz5]], [[3dz6|3dz6]], [[3dz7|3dz7]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AMD1, AMD ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AMD1, AMD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dz2 OCA], [https://pdbe.org/3dz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dz2 RCSB], [https://www.ebi.ac.uk/pdbsum/3dz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dz2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/3dz2_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/3dz2_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 3dz2" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3dz2" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[SAM decarboxylase|SAM decarboxylase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 36: | Line 39: | ||
[[Category: Adenosylmethionine decarboxylase]] | [[Category: Adenosylmethionine decarboxylase]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bale, S]] | [[Category: Bale, S]] | ||
[[Category: Ealick, S E]] | [[Category: Ealick, S E]] | ||
Revision as of 08:11, 9 February 2022
Human AdoMetDC with 5'-[(3-aminopropyl)methylamino]-5'deoxy-8-methyladenosine
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Categories: Adenosylmethionine decarboxylase | Human | Large Structures | Bale, S | Ealick, S E | Guida, W C | III, J A.Secrist | McCloskey, D E | Pegg, A E | Complexes of adometdc with 8-substituted ligand | Decarboxylase | Lyase | Pyruvate | S-adenosyl-l-methionine | Spermidine biosynthesis | Zymogen

