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2mla
From Proteopedia
(Difference between revisions)
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<StructureSection load='2mla' size='340' side='right'caption='[[2mla]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2mla' size='340' side='right'caption='[[2mla]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mla]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2mla]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLA FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mla OCA], [https://pdbe.org/2mla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mla RCSB], [https://www.ebi.ac.uk/pdbsum/2mla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mla ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KAX36_MESMA KAX36_MESMA]] Blocks voltage-gated potassium channels. At 2 uM, blocks rat Kv1.1/KCNA1 and Kv1.3/KCNA3, has a strong effect on rat Kv1.2/KCNA2 and Kv1.6/KCNA6 as well as a moderate effect on Shaker IR.<ref>PMID:9354615</ref> <ref>PMID:20713119</ref> |
==See Also== | ==See Also== | ||
Revision as of 11:36, 16 February 2022
Solution structure of BmKTX-D19K
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Categories: Buthus martensi | Large Structures | Chen, Z | Hong, J | Lin, D | Wu, Y | Toxin
