TGF beta signaling pathway

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<StructureSection load='1ktz' size='340' side='right' caption='Human hTGFR-II extracellular domain (green) complex with TGF-β3 (grey) (PDB code [[1ktz]])' scene=''>
<StructureSection load='1ktz' size='340' side='right' caption='Human hTGFR-II extracellular domain (green) complex with TGF-β3 (grey) (PDB code [[1ktz]])' scene=''>
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==The TGF beta superfamily of ligands==
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===Bone morphogenetic protein===
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[[Bone morphogenetic protein]]
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BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]].
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==[[TGF-beta receptor]]==
==[[TGF-beta receptor]]==
'''TGF-β receptors''' (Transforming Growth Factor) (TGFR) are serine/threonine kinase receptors. They are involved in paracrine signaling and are found in many types of tissue. TGF-β ligands include bone morphogenetic proteins, growth and initiation factors, anti-Mullerian hormone, activin, nodal TGF-β<ref>PMID:9525694</ref>. There are 3 types of TGFR: <br />
'''TGF-β receptors''' (Transforming Growth Factor) (TGFR) are serine/threonine kinase receptors. They are involved in paracrine signaling and are found in many types of tissue. TGF-β ligands include bone morphogenetic proteins, growth and initiation factors, anti-Mullerian hormone, activin, nodal TGF-β<ref>PMID:9525694</ref>. There are 3 types of TGFR: <br />

Revision as of 14:33, 16 February 2022

Human hTGFR-II extracellular domain (green) complex with TGF-β3 (grey) (PDB code 1ktz)

Drag the structure with the mouse to rotate

References

  1. Wrana JL. TGF-beta receptors and signalling mechanisms. Miner Electrolyte Metab. 1998;24(2-3):120-30. PMID:9525694

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Alexander Berchansky

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