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3f4n
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis== | ==Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis== | ||
| - | <StructureSection load='3f4n' size='340' side='right' caption='[[3f4n]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='3f4n' size='340' side='right'caption='[[3f4n]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3f4n]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3f4n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F4N FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PXP:PYRIDOXINE-5-PHOSPHATE'>PXP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PXP:PYRIDOXINE-5-PHOSPHATE'>PXP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pdxJ, y1300, YPO2930, YP_2525 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pdxJ, y1300, YPO2930, YP_2525 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyridoxine_5'-phosphate_synthase Pyridoxine 5'-phosphate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.99.2 2.6.99.2] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f4n OCA], [https://pdbe.org/3f4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f4n RCSB], [https://www.ebi.ac.uk/pdbsum/3f4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f4n ProSAT], [https://www.topsan.org/Proteins/CSGID/3f4n TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PDXJ_YERPE PDXJ_YERPE]] Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pyridoxine 5'-phosphate synthase]] | [[Category: Pyridoxine 5'-phosphate synthase]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
Revision as of 09:23, 23 February 2022
Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis
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Categories: Large Structures | Pyridoxine 5'-phosphate synthase | Anderson, W F | Structural genomic | Joachimiak, A | Kim, Y | Maltseva, N | Stam, J | Biosynthetic protein | Csgid | National project on protein structural and functional analyse | Nppsfa | Octamer | Pyridoxine biosynthesis | Tim barrel | Transferase
