This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1x40
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='1x40' size='340' side='right'caption='[[1x40]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1x40' size='340' side='right'caption='[[1x40]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1x40]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1x40]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X40 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0580 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0580 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x40 OCA], [https://pdbe.org/1x40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x40 RCSB], [https://www.ebi.ac.uk/pdbsum/1x40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x40 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x40 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ARAP2_HUMAN ARAP2_HUMAN]] Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:03, 2 March 2022
Solution structure of the SAM domain of human ARAP2
| |||||||||||
Categories: Human | Large Structures | Inoue, M | Kigawa, T | Koshiba, S | Structural genomic | Sasagawa, A | Tochio, N | Yokoyama, S | Asap-related protein2 | Gtpase activity | National project on protein structural and functional analyse | Nppsfa | Rsgi | Sam domain | Signal transduction | Unknown function
