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1zkh
From Proteopedia
(Difference between revisions)
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<StructureSection load='1zkh' size='340' side='right'caption='[[1zkh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1zkh' size='340' side='right'caption='[[1zkh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1zkh]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1zkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZKH FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SF3A1, SAP114 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SF3A1, SAP114 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zkh OCA], [https://pdbe.org/1zkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zkh RCSB], [https://www.ebi.ac.uk/pdbsum/1zkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zkh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN]] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:17, 2 March 2022
Solution structure of a human ubiquitin-like domain in SF3A1
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Categories: Human | Large Structures | Arrowsmith, C H | Avvakumov, G V | Dhe-Paganon, S | Edwards, A | Guido, V | Lemak, A | Lukin, J A | Mackenzie, F | Newman, E M | Structural genomic | Sundstrom, M | Xue, S | Gene regulation | Sgc | Splicing factor | Ubiquitin
