3ftj

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==Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans==
==Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans==
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<StructureSection load='3ftj' size='340' side='right' caption='[[3ftj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3ftj' size='340' side='right'caption='[[3ftj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ftj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FTJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ftj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTJ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">macB, MACB_ACTAC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=714 "Bacterium acetinomycetum comitans" (sic) (Klinger 1912) Colebrook 1920])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">macB, MACB_ACTAC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=714 "Bacterium acetinomycetum comitans" (sic) (Klinger 1912) Colebrook 1920])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ftj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ftj OCA], [http://pdbe.org/3ftj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ftj RCSB], [http://www.ebi.ac.uk/pdbsum/3ftj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ftj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ftj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ftj OCA], [https://pdbe.org/3ftj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ftj RCSB], [https://www.ebi.ac.uk/pdbsum/3ftj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ftj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MACB_AGGAC MACB_AGGAC]] Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<ref>PMID:19432486</ref>
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[[https://www.uniprot.org/uniprot/MACB_AGGAC MACB_AGGAC]] Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<ref>PMID:19432486</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Ha, N C]]
[[Category: Ha, N C]]
[[Category: Xu, Y]]
[[Category: Xu, Y]]

Revision as of 08:10, 2 March 2022

Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans

PDB ID 3ftj

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