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3fwx

From Proteopedia

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{{Seed}}
 
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[[Image:3fwx.png|left|200px]]
 
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<!--
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==The crystal structure of the peptide deformylase from Vibrio cholerae O1 biovar El Tor str. N16961==
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The line below this paragraph, containing "STRUCTURE_3fwx", creates the "Structure Box" on the page.
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<StructureSection load='3fwx' size='340' side='right'caption='[[3fwx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fwx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibc3 Vibc3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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-->
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3fwx| PDB=3fwx | SCENE= }}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">def-1, GI:15640078, VC0395_A2473 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=345073 VIBC3])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwx OCA], [https://pdbe.org/3fwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwx RCSB], [https://www.ebi.ac.uk/pdbsum/3fwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwx ProSAT], [https://www.topsan.org/Proteins/CSGID/3fwx TOPSAN]</span></td></tr>
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===The crystal structure of the peptide deformylase from Vibrio cholerae O1 biovar El Tor str. N16961===
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/A5F4B3_VIBC3 A5F4B3_VIBC3]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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==About this Structure==
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== Evolutionary Conservation ==
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3FWX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o395 Vibrio cholerae o395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWX OCA].
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Vibrio cholerae o395]]
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Check<jmol>
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[[Category: Anderson, W.]]
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<jmolCheckbox>
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwx_consurf.spt"</scriptWhenChecked>
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[[Category: Joachimiak, A.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Stam, J.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Zhang, R.]]
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</jmolCheckbox>
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[[Category: Zhou, M.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwx ConSurf].
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[[Category: Center for structural genomics of infectious disease]]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Vibc3]]
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[[Category: Anderson, W]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak, A]]
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[[Category: Stam, J]]
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[[Category: Zhang, R]]
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[[Category: Zhou, M]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Niaid structural genomic]]
 
[[Category: Peptide deformylase]]
[[Category: Peptide deformylase]]
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[[Category: Structural genomic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:24:37 2009''
 

Current revision

The crystal structure of the peptide deformylase from Vibrio cholerae O1 biovar El Tor str. N16961

PDB ID 3fwx

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